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Eomes controls the development of Th17-derived (non-classic) Th1 cells during chronic inflammation.
Mazzoni A, Maggi L, Siracusa F, Ramazzotti M, Rossi MC, Santarlasci V, Montaini G, Capone M, Rossettini B, De Palma R, Kruglov A, Chang HD, Cimaz R, Maggi E, Romagnani S, Liotta F, Cosmi L, Annunziato F. Mazzoni A, et al. Among authors: cimaz r. Eur J Immunol. 2019 Jan;49(1):79-95. doi: 10.1002/eji.201847677. Epub 2018 Nov 22. Eur J Immunol. 2019. PMID: 30144030 Free article.
Rarity of human T helper 17 cells is due to retinoic acid orphan receptor-dependent mechanisms that limit their expansion.
Santarlasci V, Maggi L, Capone M, Querci V, Beltrame L, Cavalieri D, D'Aiuto E, Cimaz R, Nebbioso A, Liotta F, De Palma R, Maggi E, Cosmi L, Romagnani S, Annunziato F. Santarlasci V, et al. Among authors: cimaz r. Immunity. 2012 Feb 24;36(2):201-14. doi: 10.1016/j.immuni.2011.12.013. Epub 2012 Feb 9. Immunity. 2012. PMID: 22326581 Free article.
Distinctive features of classic and nonclassic (Th17 derived) human Th1 cells.
Maggi L, Santarlasci V, Capone M, Rossi MC, Querci V, Mazzoni A, Cimaz R, De Palma R, Liotta F, Maggi E, Romagnani S, Cosmi L, Annunziato F. Maggi L, et al. Among authors: cimaz r. Eur J Immunol. 2012 Dec;42(12):3180-8. doi: 10.1002/eji.201242648. Epub 2012 Oct 25. Eur J Immunol. 2012. PMID: 22965818 Free article. Clinical Trial.
Brief report: etanercept inhibits the tumor necrosis factor α-driven shift of Th17 lymphocytes toward a nonclassic Th1 phenotype in juvenile idiopathic arthritis.
Maggi L, Cimaz R, Capone M, Santarlasci V, Querci V, Simonini G, Nencini F, Liotta F, Romagnani S, Maggi E, Annunziato F, Cosmi L. Maggi L, et al. Among authors: cimaz r. Arthritis Rheumatol. 2014 May;66(5):1372-7. doi: 10.1002/art.38355. Arthritis Rheumatol. 2014. PMID: 24470328 Free article.
Demethylation of the RORC2 and IL17A in human CD4+ T lymphocytes defines Th17 origin of nonclassic Th1 cells.
Mazzoni A, Santarlasci V, Maggi L, Capone M, Rossi MC, Querci V, De Palma R, Chang HD, Thiel A, Cimaz R, Liotta F, Cosmi L, Maggi E, Radbruch A, Romagnani S, Dong J, Annunziato F. Mazzoni A, et al. Among authors: cimaz r. J Immunol. 2015 Apr 1;194(7):3116-26. doi: 10.4049/jimmunol.1401303. Epub 2015 Mar 4. J Immunol. 2015. PMID: 25740946 Free article.
Immunosuppressive Activity of Abatacept on Circulating T Helper Lymphocytes from Juvenile Idiopathic Arthritis Patients.
Maggi L, Cimaz R, Capone M, Santarlasci V, Rossi MC, Mazzoni A, Montaini G, Pagnini I, Giani T, Simonini G, Scaletti C, Liotta F, Maggi E, Annunziato F, Cosmi L. Maggi L, et al. Among authors: cimaz r. Int Arch Allergy Immunol. 2016;171(1):45-53. doi: 10.1159/000450948. Epub 2016 Nov 8. Int Arch Allergy Immunol. 2016. PMID: 27820937 Free article.
Musculin inhibits human T-helper 17 cell response to interleukin 2 by controlling STAT5B activity.
Santarlasci V, Mazzoni A, Capone M, Rossi MC, Maggi L, Montaini G, Rossettini B, Cimaz R, Ramazzotti M, Barra G, De Palma R, Maggi E, Liotta F, Cosmi L, Romagnani S, Annunziato F. Santarlasci V, et al. Among authors: cimaz r. Eur J Immunol. 2017 Sep;47(9):1427-1442. doi: 10.1002/eji.201746996. Epub 2017 Jul 6. Eur J Immunol. 2017. PMID: 28612433 Free article.
Th17 lymphocyte-dependent degradation of joint cartilage by synovial fibroblasts in a humanized mouse model of arthritis and reversal by secukinumab.
Margheri F, Maggi L, Biagioni A, Chillà A, Laurenzana A, Bianchini F, Bani D, Capone M, Mazzoni A, Rossi MC, Liotta F, Cosmi L, Giani T, Cimaz R, Fibbi G, Annunziato F, Del Rosso M. Margheri F, et al. Among authors: cimaz r. Eur J Immunol. 2021 Jan;51(1):220-230. doi: 10.1002/eji.202048773. Epub 2020 Aug 9. Eur J Immunol. 2021. PMID: 32691428 Free article.
Antigen-driven PD-1+ TOX+ BHLHE40+ and PD-1+ TOX+ EOMES+ T lymphocytes regulate juvenile idiopathic arthritis in situ.
Maschmeyer P, Heinz GA, Skopnik CM, Lutter L, Mazzoni A, Heinrich F, von Stuckrad SL, Wirth LE, Tran CL, Riedel R, Lehmann K, Sakwa I, Cimaz R, Giudici F, Mall MA, Enghard P, Vastert B, Chang HD, Durek P, Annunziato F, van Wijk F, Radbruch A, Kallinich T, Mashreghi MF. Maschmeyer P, et al. Among authors: cimaz r. Eur J Immunol. 2021 Apr;51(4):915-929. doi: 10.1002/eji.202048797. Epub 2021 Feb 2. Eur J Immunol. 2021. PMID: 33296081 Free article.
461 results