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Amelioration of PXR-mediated CYP3A4 induction by mGluR2 modulators.
Vaz RJ, Li Y, Chellaraj V, Reiling S, Kuntzweiler T, Yang D, Shen H, Batchelor JD, Zhang Y, Chen X, McLean LR, Kosley R Jr. Vaz RJ, et al. Among authors: reiling s. Bioorg Med Chem Lett. 2018 Oct 15;28(19):3194-3196. doi: 10.1016/j.bmcl.2018.08.022. Epub 2018 Aug 20. Bioorg Med Chem Lett. 2018. PMID: 30146095
Dependence on the Pyrimidine Biosynthetic Enzyme DHODH Is a Synthetic Lethal Vulnerability in Mutant KRAS-Driven Cancers.
Koundinya M, Sudhalter J, Courjaud A, Lionne B, Touyer G, Bonnet L, Menguy I, Schreiber I, Perrault C, Vougier S, Benhamou B, Zhang B, He T, Gao Q, Gee P, Simard D, Castaldi MP, Tomlinson R, Reiling S, Barrague M, Newcombe R, Cao H, Wang Y, Sun F, Murtie J, Munson M, Yang E, Harper D, Bouaboula M, Pollard J, Grepin C, Garcia-Echeverria C, Cheng H, Adrian F, Winter C, Licht S, Cornella-Taracido I, Arrebola R, Morris A. Koundinya M, et al. Among authors: reiling s. Cell Chem Biol. 2018 Jun 21;25(6):705-717.e11. doi: 10.1016/j.chembiol.2018.03.005. Epub 2018 Apr 5. Cell Chem Biol. 2018. PMID: 29628435 Free article.
47 results