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4CMenB vaccine induces elite cross-protective human antibodies that compete with human factor H for binding to meningococcal fHbp.
Veggi D, Bianchi F, Santini L, Lo Surdo P, Chesterman CC, Pansegrau W, Bechi N, Huang Y, Masignani V, Pizza M, Rappuoli R, Bottomley MJ, Cozzi R, Maione D. Veggi D, et al. Among authors: huang y. PLoS Pathog. 2020 Oct 2;16(10):e1008882. doi: 10.1371/journal.ppat.1008882. eCollection 2020 Oct. PLoS Pathog. 2020. PMID: 33007046 Free PMC article.
Convergent structural features of respiratory syncytial virus neutralizing antibodies and plasticity of the site V epitope on prefusion F.
Harshbarger W, Tian S, Wahome N, Balsaraf A, Bhattacharya D, Jiang D, Pandey R, Tungare K, Friedrich K, Mehzabeen N, Biancucci M, Chinchilla-Olszar D, Mallett CP, Huang Y, Wang Z, Bottomley MJ, Malito E, Chandramouli S. Harshbarger W, et al. Among authors: huang y. PLoS Pathog. 2020 Nov 2;16(11):e1008943. doi: 10.1371/journal.ppat.1008943. eCollection 2020 Nov. PLoS Pathog. 2020. PMID: 33137810 Free PMC article.
Structural and computational design of a SARS-CoV-2 spike antigen with improved expression and immunogenicity.
Williams JA, Biancucci M, Lessen L, Tian S, Balsaraf A, Chen L, Chesterman C, Maruggi G, Vandepaer S, Huang Y, Mallett CP, Steff AM, Bottomley MJ, Malito E, Wahome N, Harshbarger WD. Williams JA, et al. Among authors: huang y. Sci Adv. 2023 Jun 9;9(23):eadg0330. doi: 10.1126/sciadv.adg0330. Epub 2023 Jun 7. Sci Adv. 2023. PMID: 37285422 Free PMC article.
Bactericidal human monoclonal antibody 1B1 shows specificity for meningococcal factor H binding protein variant 2 and displaces human factor H.
Veggi D, Chesterman CC, Santini L, Huang Y, Pacchiani N, Sierra J, Chen L, Laliberte J, Bianchi F, Cozzi R, Frigimelica E, Maione D, Finco O, Bottomley MJ. Veggi D, et al. Among authors: huang y. FASEB Bioadv. 2024 Jun 27;6(8):235-248. doi: 10.1096/fba.2023-00077. eCollection 2024 Aug. FASEB Bioadv. 2024. PMID: 39114449 Free PMC article.
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