Grandér D - Search Results

1

Metabolic reprogramming of acute lymphoblastic leukemia cells in response to glucocorticoid treatment.

Dyczynski M, Vesterlund M, Björklund AC, Zachariadis V, Janssen J, Gallart-Ayala H, Daskalaki E, Wheelock CE, Lehtiö J, Grandér D, Tamm KP, Nilsson R. Dyczynski M, et al. Among authors: grander d. Cell Death Dis. 2018 Aug 28;9(9):846. doi: 10.1038/s41419-018-0625-7. Cell Death Dis. 2018. PMID: 30154400 Free PMC article.

2

Interferon alpha induces nucleus-independent apoptosis by activating extracellular signal-regulated kinase 1/2 and c-Jun NH2-terminal kinase downstream of phosphatidylinositol 3-kinase and mammalian target of rapamycin.

Panaretakis T, Hjortsberg L, Tamm KP, Björklund AC, Joseph B, Grandér D. Panaretakis T, et al. Among authors: grander d. Mol Biol Cell. 2008 Jan;19(1):41-50. doi: 10.1091/mbc.e07-04-0358. Epub 2007 Oct 17. Mol Biol Cell. 2008. PMID: 17942603 Free PMC article.

3

Activation of STAT1 is required for interferon-alpha-mediated cell death.

Arulampalam V, Kolosenko I, Hjortsberg L, Björklund AC, Grandér D, Tamm KP. Arulampalam V, et al. Among authors: grander d. Exp Cell Res. 2011 Jan 1;317(1):9-19. doi: 10.1016/j.yexcr.2010.10.002. Epub 2010 Oct 16. Exp Cell Res. 2011. PMID: 20937272

4

An activated JAK/STAT3 pathway and CD45 expression are associated with sensitivity to Hsp90 inhibitors in multiple myeloma.

Lin H, Kolosenko I, Björklund AC, Protsyuk D, Österborg A, Grandér D, Tamm KP. Lin H, et al. Among authors: grander d. Exp Cell Res. 2013 Mar 10;319(5):600-11. doi: 10.1016/j.yexcr.2012.12.006. Epub 2012 Dec 13. Exp Cell Res. 2013. PMID: 23246572

5

RNAi prodrugs targeting Plk1 induce specific gene silencing in primary cells from pediatric T-acute lymphoblastic leukemia patients.

Kolosenko I, Edsbäcker E, Björklund AC, Hamil AS, Goroshchuk O, Grandér D, Dowdy SF, Palm-Apergi C. Kolosenko I, et al. Among authors: grander d. J Control Release. 2017 Sep 10;261:199-206. doi: 10.1016/j.jconrel.2017.07.002. Epub 2017 Jul 3. J Control Release. 2017. PMID: 28684168

6

An antisense RNA capable of modulating the expression of the tumor suppressor microRNA-34a.

Serviss JT, Andrews N, Van den Eynden J, Richter FC, Houtman M, Vesterlund M, Schwarzmueller L, Johnsson P, Larsson E, Grandér D, Pokrovskaja Tamm K. Serviss JT, et al. Among authors: grander d. Cell Death Dis. 2018 Jul 3;9(7):736. doi: 10.1038/s41419-018-0777-5. Cell Death Dis. 2018. PMID: 29970884 Free PMC article.

7

Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy.

Laane E, Tamm KP, Buentke E, Ito K, Kharaziha P, Oscarsson J, Corcoran M, Björklund AC, Hultenby K, Lundin J, Heyman M, Söderhäll S, Mazur J, Porwit A, Pandolfi PP, Zhivotovsky B, Panaretakis T, Grandér D. Laane E, et al. Among authors: grander d. Cell Death Differ. 2009 Jul;16(7):1018-29. doi: 10.1038/cdd.2009.46. Epub 2009 Apr 24. Cell Death Differ. 2009. PMID: 19390558

8

Doxorubicin requires the sequential activation of caspase-2, protein kinase Cdelta, and c-Jun NH2-terminal kinase to induce apoptosis.

Panaretakis T, Laane E, Pokrovskaja K, Björklund AC, Moustakas A, Zhivotovsky B, Heyman M, Shoshan MC, Grandér D. Panaretakis T, et al. Among authors: grander d. Mol Biol Cell. 2005 Aug;16(8):3821-31. doi: 10.1091/mbc.e04-10-0862. Epub 2005 May 25. Mol Biol Cell. 2005. PMID: 15917298 Free PMC article.

9

Identification of novel small molecules that inhibit STAT3-dependent transcription and function.

Kolosenko I, Yu Y, Busker S, Dyczynski M, Liu J, Haraldsson M, Palm Apergi C, Helleday T, Tamm KP, Page BDG, Grander D. Kolosenko I, et al. Among authors: grander d. PLoS One. 2017 Jun 21;12(6):e0178844. doi: 10.1371/journal.pone.0178844. eCollection 2017. PLoS One. 2017. PMID: 28636670 Free PMC article.

10

Cell crowding induces interferon regulatory factor 9, which confers resistance to chemotherapeutic drugs.

Kolosenko I, Fryknäs M, Forsberg S, Johnsson P, Cheon H, Holvey-Bates EG, Edsbäcker E, Pellegrini P, Rassoolzadeh H, Brnjic S, Larsson R, Stark GR, Grandér D, Linder S, Tamm KP, De Milito A. Kolosenko I, et al. Among authors: grander d. Int J Cancer. 2015 Feb 15;136(4):E51-61. doi: 10.1002/ijc.29161. Epub 2014 Sep 4. Int J Cancer. 2015. PMID: 25156627

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