Zhang Y - Search Results

1

Structure-Activity Relationship Studies of 6α- and 6β-Indolylacetamidonaltrexamine Derivatives as Bitopic Mu Opioid Receptor Modulators and Elaboration of the "Message-Address Concept" To Comprehend Their Functional Conversion.

Obeng S, Wang H, Jali A, Stevens DL, Akbarali HI, Dewey WL, Selley DE, Zhang Y. Obeng S, et al. Among authors: zhang y. ACS Chem Neurosci. 2019 Mar 20;10(3):1075-1090. doi: 10.1021/acschemneuro.8b00349. Epub 2018 Sep 7. ACS Chem Neurosci. 2019. PMID: 30156823 Free PMC article.

2

Antinociceptive Interactions between the Imidazoline I2 Receptor Agonist 2-BFI and Opioids in Rats: Role of Efficacy at the μ-Opioid Receptor.

Siemian JN, Obeng S, Zhang Y, Zhang Y, Li JX. Siemian JN, et al. Among authors: zhang y. J Pharmacol Exp Ther. 2016 Jun;357(3):509-19. doi: 10.1124/jpet.116.232421. Epub 2016 Apr 7. J Pharmacol Exp Ther. 2016. PMID: 27056847 Free PMC article.

3

Nanoconjugated NAP as a Potent and Periphery Selective Mu Opioid Receptor Modulator To Treat Opioid-Induced Constipation.

Xu GG, Zolotarskaya OY, Williams DA, Yuan Y, Selley DE, Dewey WL, Akbarali HI, Yang H, Zhang Y. Xu GG, et al. Among authors: zhang y. ACS Med Chem Lett. 2016 Nov 21;8(1):78-83. doi: 10.1021/acsmedchemlett.6b00382. eCollection 2017 Jan 12. ACS Med Chem Lett. 2016. PMID: 28105279 Free PMC article.

4

Binding mode analyses of NAP derivatives as mu opioid receptor selective ligands through docking studies and molecular dynamics simulation.

Wang H, Zaidi SA, Zhang Y. Wang H, et al. Among authors: zhang y. Bioorg Med Chem. 2017 Apr 15;25(8):2463-2471. doi: 10.1016/j.bmc.2017.03.005. Epub 2017 Mar 6. Bioorg Med Chem. 2017. PMID: 28302509 Free PMC article.

5

Diaminopimelic acid (DAP) analogs bearing isoxazoline moiety as selective inhibitors against meso-diaminopimelate dehydrogenase (m-Ddh) from Porphyromonas gingivalis.

Ma H, Stone VN, Wang H, Kellogg GE, Xu P, Zhang Y. Ma H, et al. Among authors: zhang y. Bioorg Med Chem Lett. 2017 Aug 15;27(16):3840-3844. doi: 10.1016/j.bmcl.2017.06.056. Epub 2017 Jun 22. Bioorg Med Chem Lett. 2017. PMID: 28668193 Free PMC article.

6

Understanding molecular interactions between scavenger receptor A and its natural product inhibitors through molecular modeling studies.

Pagare PP, Zaidi SA, Zhang X, Li X, Yu X, Wang XY, Zhang Y. Pagare PP, et al. Among authors: zhang x, zhang y. J Mol Graph Model. 2017 Oct;77:189-199. doi: 10.1016/j.jmgm.2017.08.013. Epub 2017 Aug 16. J Mol Graph Model. 2017. PMID: 28869863 Free PMC article.

7

Application of Receptor Theory to the Design and Use of Fixed-Proportion Mu-Opioid Agonist and Antagonist Mixtures in Rhesus Monkeys.

Cornelissen JC, Obeng S, Rice KC, Zhang Y, Negus SS, Banks ML. Cornelissen JC, et al. Among authors: zhang y. J Pharmacol Exp Ther. 2018 Apr;365(1):37-47. doi: 10.1124/jpet.117.246439. Epub 2018 Jan 12. J Pharmacol Exp Ther. 2018. PMID: 29330156 Free PMC article.

8

In vitro and in vivo functional profile characterization of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(isoquinoline-3-carboxamido)morphinan (NAQ) as a low efficacy mu opioid receptor modulator.

Obeng S, Yuan Y, Jali A, Selley DE, Zhang Y. Obeng S, et al. Among authors: zhang y. Eur J Pharmacol. 2018 May 15;827:32-40. doi: 10.1016/j.ejphar.2018.03.013. Epub 2018 Mar 9. Eur J Pharmacol. 2018. PMID: 29530590 Free PMC article.

9

Exploring the binding mechanisms of diaminopimelic acid analogs to meso-diaminopimelate dehydrogenase by molecular modeling.

Wang H, Kellogg GE, Xu P, Zhang Y. Wang H, et al. Among authors: zhang y. J Mol Graph Model. 2018 Aug;83:100-111. doi: 10.1016/j.jmgm.2018.05.011. Epub 2018 Jun 2. J Mol Graph Model. 2018. PMID: 29885593 Free PMC article.

10

Methylation Products of 6β- N-Heterocyclic Substituted Naltrexamine Derivatives as Potential Peripheral Opioid Receptor Modulators.

Zheng Y, Obeng S, Wang H, Stevens DL, Komla E, Selley DE, Dewey WL, Akbarali HI, Zhang Y. Zheng Y, et al. Among authors: zhang y. ACS Chem Neurosci. 2018 Dec 19;9(12):3028-3037. doi: 10.1021/acschemneuro.8b00234. Epub 2018 Jul 23. ACS Chem Neurosci. 2018. PMID: 30001114 Free PMC article.

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