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Pediatric patients with acute lymphoblastic leukemia generate abundant and functional neoantigen-specific CD8+ T cell responses.
Zamora AE, Crawford JC, Allen EK, Guo XJ, Bakke J, Carter RA, Abdelsamed HA, Moustaki A, Li Y, Chang TC, Awad W, Dallas MH, Mullighan CG, Downing JR, Geiger TL, Chen T, Green DR, Youngblood BA, Zhang J, Thomas PG. Zamora AE, et al. Sci Transl Med. 2019 Jun 26;11(498):eaat8549. doi: 10.1126/scitranslmed.aat8549. Sci Transl Med. 2019. PMID: 31243155 Free PMC article.
A population of proinflammatory T cells coexpresses αβ and γδ T cell receptors in mice and humans.
Edwards SC, Sutton CE, Ladell K, Grant EJ, McLaren JE, Roche F, Dash P, Apiwattanakul N, Awad W, Miners KL, Lalor SJ, Ribot JC, Baik S, Moran B, McGinley A, Pivorunas V, Dowding L, Macoritto M, Paez-Cortez J, Slavin A, Anderson G, Silva-Santos B, Hokamp K, Price DA, Thomas PG, McLoughlin RM, Mills KHG. Edwards SC, et al. J Exp Med. 2020 May 4;217(5):e20190834. doi: 10.1084/jem.20190834. J Exp Med. 2020. PMID: 32106283 Free PMC article.
Cross-reactive Antibody Response to mRNA SARS-CoV-2 Vaccine After Recent COVID-19-Specific Monoclonal Antibody Therapy.
Schultz-Cherry S, McGargill MA, Thomas PG, Estepp JH, Gaur AH, Allen EK, Allison KJ, Tang L, Webby RJ, Cherry SD, Lin CY, Fabrizio T, Tuomanen EI, Wolf J; SJTRC Investigative Team. Schultz-Cherry S, et al. Open Forum Infect Dis. 2021 Aug 10;8(9):ofab420. doi: 10.1093/ofid/ofab420. eCollection 2021 Sep. Open Forum Infect Dis. 2021. PMID: 34557558 Free PMC article.
Host Predictors of Broadly Cross-Reactive Antibodies Against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Variants of Concern Differ Between Infection and Vaccination.
Tang L, Cherry S, Tuomanen EI, Kirkpatrick Roubidoux E, Lin CY, Allison KJ, Gowen A, Freiden P, Allen EK, Su Y, Gaur AH, Estepp JH, McGargill MA, Krammer F, Thomas PG, Schultz-Cherry S, Wolf J; St. Jude Investigative Team. Tang L, et al. Clin Infect Dis. 2022 Aug 24;75(1):e705-e714. doi: 10.1093/cid/ciab996. Clin Infect Dis. 2022. PMID: 34891165 Free PMC article.
Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response.
Lin CY, Wolf J, Brice DC, Sun Y, Locke M, Cherry S, Castellaw AH, Wehenkel M, Crawford JC, Zarnitsyna VI, Duque D, Allison KJ, Allen EK, Brown SA, Mandarano AH, Estepp JH; SJTRC Study Team; Taylor C, Molina-Paris C, Schultz-Cherry S, Tang L, Thomas PG, McGargill MA. Lin CY, et al. Cell Host Microbe. 2022 Jan 12;30(1):83-96.e4. doi: 10.1016/j.chom.2021.12.005. Epub 2021 Dec 7. Cell Host Microbe. 2022. PMID: 34965382 Free PMC article.
SARS-CoV-2 mRNA vaccination elicits a robust and persistent T follicular helper cell response in humans.
Mudd PA, Minervina AA, Pogorelyy MV, Turner JS, Kim W, Kalaidina E, Petersen J, Schmitz AJ, Lei T, Haile A, Kirk AM, Mettelman RC, Crawford JC, Nguyen THO, Rowntree LC, Rosati E, Richards KA, Sant AJ, Klebert MK, Suessen T, Middleton WD; SJTRC Study Team; Wolf J, Teefey SA, O'Halloran JA, Presti RM, Kedzierska K, Rossjohn J, Thomas PG, Ellebedy AH. Mudd PA, et al. Cell. 2022 Feb 17;185(4):603-613.e15. doi: 10.1016/j.cell.2021.12.026. Epub 2021 Dec 23. Cell. 2022. PMID: 35026152 Free PMC article.
SARS-CoV-2 antigen exposure history shapes phenotypes and specificity of memory CD8+ T cells.
Minervina AA, Pogorelyy MV, Kirk AM, Crawford JC, Allen EK, Chou CH, Mettelman RC, Allison KJ, Lin CY, Brice DC, Zhu X, Vegesana K, Wu G, Trivedi S, Kottapalli P, Darnell D, McNeely S, Olsen SR, Schultz-Cherry S, Estepp JH; SJTRC Study Team; McGargill MA, Wolf J, Thomas PG. Minervina AA, et al. Nat Immunol. 2022 May;23(5):781-790. doi: 10.1038/s41590-022-01184-4. Epub 2022 Apr 5. Nat Immunol. 2022. PMID: 35383307 Free PMC article.
70 results