van Vugt MATM - Search Results

1

TPX2/Aurora kinase A signaling as a potential therapeutic target in genomically unstable cancer cells.

van Gijn SE, Wierenga E, van den Tempel N, Kok YP, Heijink AM, Spierings DCJ, Foijer F, van Vugt MATM, Fehrmann RSN. van Gijn SE, et al. Among authors: van vugt matm, van den tempel n. Oncogene. 2019 Feb;38(6):852-867. doi: 10.1038/s41388-018-0470-2. Epub 2018 Sep 3. Oncogene. 2019. PMID: 30177840 Free PMC article.

2

Getting in and out of mitosis with Polo-like kinase-1.

van Vugt MA, Medema RH. van Vugt MA, et al. Oncogene. 2005 Apr 18;24(17):2844-59. doi: 10.1038/sj.onc.1208617. Oncogene. 2005. PMID: 15838519 Review.

3

Loss of Rb proteins causes genomic instability in the absence of mitogenic signaling.

van Harn T, Foijer F, van Vugt M, Banerjee R, Yang F, Oostra A, Joenje H, te Riele H. van Harn T, et al. Genes Dev. 2010 Jul 1;24(13):1377-88. doi: 10.1101/gad.580710. Epub 2010 Jun 15. Genes Dev. 2010. PMID: 20551164 Free PMC article.

4

Forced activation of Cdk1 via wee1 inhibition impairs homologous recombination.

Krajewska M, Heijink AM, Bisselink YJ, Seinstra RI, Silljé HH, de Vries EG, van Vugt MA. Krajewska M, et al. Oncogene. 2013 Jun 13;32(24):3001-8. doi: 10.1038/onc.2012.296. Epub 2012 Jul 16. Oncogene. 2013. PMID: 22797065

5

The DNA damage response during mitosis.

Heijink AM, Krajewska M, van Vugt MA. Heijink AM, et al. Mutat Res. 2013 Oct;750(1-2):45-55. doi: 10.1016/j.mrfmmm.2013.07.003. Epub 2013 Jul 21. Mutat Res. 2013. PMID: 23880065 Review.

6

Checkpoint kinase 2 (Chk2) supports sensitivity to platinum-based treatment in high grade serous ovarian cancer.

Alkema NG, Tomar T, van der Zee AG, Everts M, Meersma GJ, Hollema H, de Jong S, van Vugt MA, Wisman GB. Alkema NG, et al. Gynecol Oncol. 2014 Jun;133(3):591-8. doi: 10.1016/j.ygyno.2014.03.557. Epub 2014 Mar 20. Gynecol Oncol. 2014. PMID: 24657486

7

ATR inhibition preferentially targets homologous recombination-deficient tumor cells.

Krajewska M, Fehrmann RS, Schoonen PM, Labib S, de Vries EG, Franke L, van Vugt MA. Krajewska M, et al. Oncogene. 2015 Jun;34(26):3474-81. doi: 10.1038/onc.2014.276. Epub 2014 Sep 1. Oncogene. 2015. PMID: 25174396

8

Gene expression analysis identifies global gene dosage sensitivity in cancer.

Fehrmann RS, Karjalainen JM, Krajewska M, Westra HJ, Maloney D, Simeonov A, Pers TH, Hirschhorn JN, Jansen RC, Schultes EA, van Haagen HH, de Vries EG, te Meerman GJ, Wijmenga C, van Vugt MA, Franke L. Fehrmann RS, et al. Nat Genet. 2015 Feb;47(2):115-25. doi: 10.1038/ng.3173. Epub 2015 Jan 12. Nat Genet. 2015. PMID: 25581432

9

Regulators of homologous recombination repair as novel targets for cancer treatment.

Krajewska M, Fehrmann RS, de Vries EG, van Vugt MA. Krajewska M, et al. Front Genet. 2015 Mar 20;6:96. doi: 10.3389/fgene.2015.00096. eCollection 2015. Front Genet. 2015. PMID: 25852742 Free PMC article. Review.

10

Targeting of β1 integrins impairs DNA repair for radiosensitization of head and neck cancer cells.

Dickreuter E, Eke I, Krause M, Borgmann K, van Vugt MA, Cordes N. Dickreuter E, et al. Oncogene. 2016 Mar 17;35(11):1353-62. doi: 10.1038/onc.2015.212. Epub 2015 Jun 15. Oncogene. 2016. PMID: 26073085

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