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Page 1
Evolution of melanoma cross-resistance to CD8+ T cells and MAPK inhibition in the course of BRAFi treatment.
Pieper N, Zaremba A, Leonardelli S, Harbers FN, Schwamborn M, Lübcke S, Schrörs B, Baingo J, Schramm A, Haferkamp S, Seifert U, Sucker A, Lennerz V, Wölfel T, Schadendorf D, Schilling B, Paschen A, Zhao F. Pieper N, et al. Among authors: seifert u. Oncoimmunology. 2018 Apr 18;7(8):e1450127. doi: 10.1080/2162402X.2018.1450127. eCollection 2018. Oncoimmunology. 2018. PMID: 30221038 Free PMC article.
The efficiency of human cytomegalovirus pp65(495-503) CD8+ T cell epitope generation is determined by the balanced activities of cytosolic and endoplasmic reticulum-resident peptidases.
Urban S, Textoris-Taube K, Reimann B, Janek K, Dannenberg T, Ebstein F, Seifert C, Zhao F, Kessler JH, Halenius A, Henklein P, Paschke J, Cadel S, Bernhard H, Ossendorp F, Foulon T, Schadendorf D, Paschen A, Seifert U. Urban S, et al. Among authors: seifert u, seifert c. J Immunol. 2012 Jul 15;189(2):529-38. doi: 10.4049/jimmunol.1101886. Epub 2012 Jun 15. J Immunol. 2012. PMID: 22706083
The proteasome immunosubunits, PA28 and ER-aminopeptidase 1 protect melanoma cells from efficient MART-126-35 -specific T-cell recognition.
Keller M, Ebstein F, Bürger E, Textoris-Taube K, Gorny X, Urban S, Zhao F, Dannenberg T, Sucker A, Keller C, Saveanu L, Krüger E, Rothkötter HJ, Dahlmann B, Henklein P, Voigt A, Kuckelkorn U, Paschen A, Kloetzel PM, Seifert U. Keller M, et al. Among authors: seifert u. Eur J Immunol. 2015 Dec;45(12):3257-68. doi: 10.1002/eji.201445243. Epub 2015 Oct 19. Eur J Immunol. 2015. PMID: 26399368 Free article.
Targeting the innate immunoreceptor RIG-I overcomes melanoma-intrinsic resistance to T cell immunotherapy.
Such L, Zhao F, Liu D, Thier B, Le-Trilling VTK, Sucker A, Coch C, Pieper N, Howe S, Bhat H, Kalkavan H, Ritter C, Brinkhaus R, Ugurel S, Köster J, Seifert U, Dittmer U, Schuler M, Lang KS, Kufer TA, Hartmann G, Becker JC, Horn S, Ferrone S, Liu D, Van Allen EM, Schadendorf D, Griewank K, Trilling M, Paschen A. Such L, et al. Among authors: seifert u. J Clin Invest. 2020 Aug 3;130(8):4266-4281. doi: 10.1172/JCI131572. J Clin Invest. 2020. PMID: 32427578 Free PMC article.
Proteasome inhibition potentiates Kv1.3 potassium channel expression as therapeutic target in drug-sensitive and -resistant human melanoma cells.
Cammann C, Kulla J, Wiebusch L, Walz C, Zhao F, Lowinus T, Topfstedt E, Mishra N, Henklein P, Bommhardt U, Bossaller L, Hagemeier C, Schadendorf D, Schmidt B, Paschen A, Seifert U. Cammann C, et al. Among authors: seifert u. Biomed Pharmacother. 2023 Dec;168:115635. doi: 10.1016/j.biopha.2023.115635. Epub 2023 Oct 8. Biomed Pharmacother. 2023. PMID: 37816303 Free article.
Consequences of COP9 signalosome and 26S proteasome interaction.
Huang X, Hetfeld BK, Seifert U, Kähne T, Kloetzel PM, Naumann M, Bech-Otschir D, Dubiel W. Huang X, et al. Among authors: seifert u. FEBS J. 2005 Aug;272(15):3909-17. doi: 10.1111/j.1742-4658.2005.04807.x. FEBS J. 2005. PMID: 16045761 Free article.
236 results