Markin CJ - Search Results

1

An Open-Source, Programmable Pneumatic Setup for Operation and Automated Control of Single- and Multi-Layer Microfluidic Devices.

Brower K, Puccinelli R, Markin CJ, Shimko TC, Longwell SA, Cruz B, Gomez-Sjoberg R, Fordyce PM. Brower K, et al. Among authors: markin cj. HardwareX. 2018 Apr;3:117-134. doi: 10.1016/j.ohx.2017.10.001. Epub 2017 Oct 31. HardwareX. 2018. PMID: 30221210 Free PMC article.

2

High-Throughput Affinity Measurements of Transcription Factor and DNA Mutations Reveal Affinity and Specificity Determinants.

Aditham AK, Markin CJ, Mokhtari DA, DelRosso N, Fordyce PM. Aditham AK, et al. Among authors: markin cj. Cell Syst. 2021 Feb 17;12(2):112-127.e11. doi: 10.1016/j.cels.2020.11.012. Epub 2020 Dec 22. Cell Syst. 2021. PMID: 33340452 Free article.

3

Revealing enzyme functional architecture via high-throughput microfluidic enzyme kinetics.

Markin CJ, Mokhtari DA, Sunden F, Appel MJ, Akiva E, Longwell SA, Sabatti C, Herschlag D, Fordyce PM. Markin CJ, et al. Science. 2021 Jul 23;373(6553):eabf8761. doi: 10.1126/science.abf8761. Science. 2021. PMID: 34437092 Free PMC article.

4

Decoupling of catalysis and transition state analog binding from mutations throughout a phosphatase revealed by high-throughput enzymology.

Markin CJ, Mokhtari DA, Du S, Doukov T, Sunden F, Cook JA, Fordyce PM, Herschlag D. Markin CJ, et al. Proc Natl Acad Sci U S A. 2023 Jul 18;120(29):e2219074120. doi: 10.1073/pnas.2219074120. Epub 2023 Jul 10. Proc Natl Acad Sci U S A. 2023. PMID: 37428919 Free PMC article.

5

Molecular basis for impaired DNA damage response function associated with the RAP80 ΔE81 defect.

Anamika, Markin CJ, Rout MK, Spyracopoulos L. Anamika, et al. Among authors: markin cj. J Biol Chem. 2014 May 2;289(18):12852-62. doi: 10.1074/jbc.M113.538280. Epub 2014 Mar 13. J Biol Chem. 2014. PMID: 24627472 Free PMC article.

6

Dynamics of the RING domain from human TRAF6 by 15N NMR spectroscopy: implications for biological function.

Markin CJ, Saltibus LF, Spyracopoulos L. Markin CJ, et al. Biochemistry. 2008 Sep 23;47(38):10010-7. doi: 10.1021/bi800252x. Epub 2008 Aug 30. Biochemistry. 2008. PMID: 18759459

7

Mechanism for recognition of polyubiquitin chains: balancing affinity through interplay between multivalent binding and dynamics.

Markin CJ, Xiao W, Spyracopoulos L. Markin CJ, et al. J Am Chem Soc. 2010 Aug 18;132(32):11247-58. doi: 10.1021/ja103869x. J Am Chem Soc. 2010. PMID: 20698691

8

Context-dependent remodeling of structure in two large protein fragments.

Schellenberg MJ, Ritchie DB, Wu T, Markin CJ, Spyracopoulos L, MacMillan AM. Schellenberg MJ, et al. Among authors: markin cj. J Mol Biol. 2010 Oct 1;402(4):720-30. doi: 10.1016/j.jmb.2010.08.020. Epub 2010 Aug 14. J Mol Biol. 2010. PMID: 20713060

9

Catalytic proficiency of ubiquitin conjugation enzymes: balancing pK(a) suppression, entropy, and electrostatics.

Markin CJ, Saltibus LF, Kean MJ, McKay RT, Xiao W, Spyracopoulos L. Markin CJ, et al. J Am Chem Soc. 2010 Dec 22;132(50):17775-86. doi: 10.1021/ja105267w. Epub 2010 Nov 29. J Am Chem Soc. 2010. PMID: 21114314

10

Increased precision for analysis of protein-ligand dissociation constants determined from chemical shift titrations.

Markin CJ, Spyracopoulos L. Markin CJ, et al. J Biomol NMR. 2012 Jun;53(2):125-38. doi: 10.1007/s10858-012-9630-9. Epub 2012 Apr 26. J Biomol NMR. 2012. PMID: 22534787

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