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The BACE-1 inhibitor CNP520 for prevention trials in Alzheimer's disease.
Neumann U, Ufer M, Jacobson LH, Rouzade-Dominguez ML, Huledal G, Kolly C, Lüönd RM, Machauer R, Veenstra SJ, Hurth K, Rueeger H, Tintelnot-Blomley M, Staufenbiel M, Shimshek DR, Perrot L, Frieauff W, Dubost V, Schiller H, Vogg B, Beltz K, Avrameas A, Kretz S, Pezous N, Rondeau JM, Beckmann N, Hartmann A, Vormfelde S, David OJ, Galli B, Ramos R, Graf A, Lopez Lopez C. Neumann U, et al. Among authors: galli b. EMBO Mol Med. 2018 Nov;10(11):e9316. doi: 10.15252/emmm.201809316. EMBO Mol Med. 2018. PMID: 30224383 Free PMC article. Clinical Trial.
Ionic liquid versus prodrug strategy to address formulation challenges.
Balk A, Widmer T, Wiest J, Bruhn H, Rybak JC, Matthes P, Müller-Buschbaum K, Sakalis A, Lühmann T, Berghausen J, Holzgrabe U, Galli B, Meinel L. Balk A, et al. Among authors: galli b. Pharm Res. 2015 Jun;32(6):2154-67. doi: 10.1007/s11095-014-1607-9. Epub 2014 Dec 23. Pharm Res. 2015. PMID: 25534684
Mapping the pharmaceutical design space by amorphous ionic liquid strategies.
Wiest J, Saedtler M, Balk A, Merget B, Widmer T, Bruhn H, Raccuglia M, Walid E, Picard F, Stopper H, Dekant W, Lühmann T, Sotriffer C, Galli B, Holzgrabe U, Meinel L. Wiest J, et al. Among authors: galli b. J Control Release. 2017 Dec 28;268:314-322. doi: 10.1016/j.jconrel.2017.10.040. Epub 2017 Oct 31. J Control Release. 2017. PMID: 29097303
Bioinspired co-crystals of Imatinib providing enhanced kinetic solubility.
Reggane M, Wiest J, Saedtler M, Harlacher C, Gutmann M, Zottnick SH, Piechon P, Dix I, Müller-Buschbaum K, Holzgrabe U, Meinel L, Galli B. Reggane M, et al. Among authors: galli b. Eur J Pharm Biopharm. 2018 Jul;128:290-299. doi: 10.1016/j.ejpb.2018.05.012. Epub 2018 May 4. Eur J Pharm Biopharm. 2018. PMID: 29733951
Predicting Bile and Lipid Interaction for Drug Substances.
Schlauersbach J, Kehrein J, Hanio S, Galli B, Harlacher C, Heidenreich C, Lenz B, Sotriffer C, Meinel L. Schlauersbach J, et al. Among authors: galli b. Mol Pharm. 2022 Aug 1;19(8):2868-2876. doi: 10.1021/acs.molpharmaceut.2c00227. Epub 2022 Jul 1. Mol Pharm. 2022. PMID: 35776440
69 results