Holmes G - Search Results

1

Midface and upper airway dysgenesis in FGFR2-related craniosynostosis involves multiple tissue-specific and cell cycle effects.

Holmes G, O'Rourke C, Motch Perrine SM, Lu N, van Bakel H, Richtsmeier JT, Jabs EW. Holmes G, et al. Development. 2018 Oct 5;145(19):dev166488. doi: 10.1242/dev.166488. Development. 2018. PMID: 30228104 Free PMC article.

2

Early onset of craniosynostosis in an Apert mouse model reveals critical features of this pathology.

Holmes G, Rothschild G, Roy UB, Deng CX, Mansukhani A, Basilico C. Holmes G, et al. Dev Biol. 2009 Apr 15;328(2):273-84. doi: 10.1016/j.ydbio.2009.01.026. Epub 2009 Jan 29. Dev Biol. 2009. PMID: 19389359 Free PMC article.

3

p38 Inhibition ameliorates skin and skull abnormalities in Fgfr2 Beare-Stevenson mice.

Wang Y, Zhou X, Oberoi K, Phelps R, Couwenhoven R, Sun M, Rezza A, Holmes G, Percival CJ, Friedenthal J, Krejci P, Richtsmeier JT, Huso DL, Rendl M, Jabs EW. Wang Y, et al. Among authors: holmes g. J Clin Invest. 2012 Jun;122(6):2153-64. doi: 10.1172/JCI62644. Epub 2012 May 15. J Clin Invest. 2012. PMID: 22585574 Free PMC article.

4

Mesodermal expression of Fgfr2S252W is necessary and sufficient to induce craniosynostosis in a mouse model of Apert syndrome.

Holmes G, Basilico C. Holmes G, et al. Dev Biol. 2012 Aug 15;368(2):283-93. doi: 10.1016/j.ydbio.2012.05.026. Epub 2012 Jun 1. Dev Biol. 2012. PMID: 22664175 Free PMC article.

5

The role of vertebrate models in understanding craniosynostosis.

Holmes G. Holmes G. Childs Nerv Syst. 2012 Sep;28(9):1471-81. doi: 10.1007/s00381-012-1844-3. Epub 2012 Aug 8. Childs Nerv Syst. 2012. PMID: 22872264 Review.

6

Mouse models of Apert syndrome.

Holmes G. Holmes G. Childs Nerv Syst. 2012 Sep;28(9):1505-10. doi: 10.1007/s00381-012-1872-z. Epub 2012 Aug 8. Childs Nerv Syst. 2012. PMID: 22872267

7

From shape to cells: mouse models reveal mechanisms altering palate development in Apert syndrome.

Martínez-Abadías N, Holmes G, Pankratz T, Wang Y, Zhou X, Jabs EW, Richtsmeier JT. Martínez-Abadías N, et al. Among authors: holmes g. Dis Model Mech. 2013 May;6(3):768-79. doi: 10.1242/dmm.010397. Epub 2013 Mar 8. Dis Model Mech. 2013. PMID: 23519026 Free PMC article.

8

Novel molecular pathways elicited by mutant FGFR2 may account for brain abnormalities in Apert syndrome.

Yeh E, Fanganiello RD, Sunaga DY, Zhou X, Holmes G, Rocha KM, Alonso N, Matushita H, Wang Y, Jabs EW, Passos-Bueno MR. Yeh E, et al. Among authors: holmes g. PLoS One. 2013 Apr 4;8(4):e60439. doi: 10.1371/journal.pone.0060439. Print 2013. PLoS One. 2013. PMID: 23593218 Free PMC article.

9

Morphological comparison of the craniofacial phenotypes of mouse models expressing the Apert FGFR2 S252W mutation in neural crest- or mesoderm-derived tissues.

Heuzé Y, Singh N, Basilico C, Jabs EW, Holmes G, Richtsmeier JT. Heuzé Y, et al. Among authors: holmes g. Bone. 2014 Jun;63:101-9. doi: 10.1016/j.bone.2014.03.003. Epub 2014 Mar 13. Bone. 2014. PMID: 24632501 Free PMC article.

10

BCL11B expression in intramembranous osteogenesis during murine craniofacial suture development.

Holmes G, van Bakel H, Zhou X, Losic B, Jabs EW. Holmes G, et al. Gene Expr Patterns. 2015 Jan;17(1):16-25. doi: 10.1016/j.gep.2014.12.001. Epub 2014 Dec 12. Gene Expr Patterns. 2015. PMID: 25511173 Free PMC article.

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