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Targeted genome fragmentation with CRISPR/Cas9 enables fast and efficient enrichment of small genomic regions and ultra-accurate sequencing with low DNA input (CRISPR-DS).
Nachmanson D, Lian S, Schmidt EK, Hipp MJ, Baker KT, Zhang Y, Tretiakova M, Loubet-Senear K, Kohrn BF, Salk JJ, Kennedy SR, Risques RA. Nachmanson D, et al. Among authors: kennedy sr. Genome Res. 2018 Oct;28(10):1589-1599. doi: 10.1101/gr.235291.118. Epub 2018 Sep 19. Genome Res. 2018. PMID: 30232196 Free PMC article.
Detection of ultra-rare mutations by next-generation sequencing.
Schmitt MW, Kennedy SR, Salk JJ, Fox EJ, Hiatt JB, Loeb LA. Schmitt MW, et al. Among authors: kennedy sr. Proc Natl Acad Sci U S A. 2012 Sep 4;109(36):14508-13. doi: 10.1073/pnas.1208715109. Epub 2012 Aug 1. Proc Natl Acad Sci U S A. 2012. PMID: 22853953 Free PMC article.
Detecting ultralow-frequency mutations by Duplex Sequencing.
Kennedy SR, Schmitt MW, Fox EJ, Kohrn BF, Salk JJ, Ahn EH, Prindle MJ, Kuong KJ, Shen JC, Risques RA, Loeb LA. Kennedy SR, et al. Nat Protoc. 2014 Nov;9(11):2586-606. doi: 10.1038/nprot.2014.170. Epub 2014 Oct 9. Nat Protoc. 2014. PMID: 25299156 Free PMC article.
Volatility of Mutator Phenotypes at Single Cell Resolution.
Kennedy SR, Schultz EM, Chappell TM, Kohrn B, Knowels GM, Herr AJ. Kennedy SR, et al. PLoS Genet. 2015 Apr 13;11(4):e1005151. doi: 10.1371/journal.pgen.1005151. eCollection 2015 Apr. PLoS Genet. 2015. PMID: 25868109 Free PMC article.
Werner syndrome through the lens of tissue and tumour genomics.
Tokita M, Kennedy SR, Risques RA, Chun SG, Pritchard C, Oshima J, Liu Y, Bryant-Greenwood PK, Welcsh P, Monnat RJ. Tokita M, et al. Among authors: kennedy sr. Sci Rep. 2016 Aug 25;6:32038. doi: 10.1038/srep32038. Sci Rep. 2016. PMID: 27559010 Free PMC article.
87 results