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Roquin targets mRNAs in a 3'-UTR-specific manner by different modes of regulation.
Essig K, Kronbeck N, Guimaraes JC, Lohs C, Schlundt A, Hoffmann A, Behrens G, Brenner S, Kowalska J, Lopez-Rodriguez C, Jemielity J, Holtmann H, Reiche K, Hackermüller J, Sattler M, Zavolan M, Heissmeyer V. Essig K, et al. Among authors: hoffmann a. Nat Commun. 2018 Sep 19;9(1):3810. doi: 10.1038/s41467-018-06184-3. Nat Commun. 2018. PMID: 30232334 Free PMC article.
Binding of NUFIP2 to Roquin promotes recognition and regulation of ICOS mRNA.
Rehage N, Davydova E, Conrad C, Behrens G, Maiser A, Stehklein JE, Brenner S, Klein J, Jeridi A, Hoffmann A, Lee E, Dianzani U, Willemsen R, Feederle R, Reiche K, Hackermüller J, Leonhardt H, Sharma S, Niessing D, Heissmeyer V. Rehage N, et al. Among authors: hoffmann a. Nat Commun. 2018 Jan 19;9(1):299. doi: 10.1038/s41467-017-02582-1. Nat Commun. 2018. PMID: 29352114 Free PMC article.
Adipocyte p53 coordinates the response to intermittent fasting by regulating adipose tissue immune cell landscape.
Reinisch I, Michenthaler H, Sulaj A, Moyschewitz E, Krstic J, Galhuber M, Xu R, Riahi Z, Wang T, Vujic N, Amor M, Zenezini Chiozzi R, Wabitsch M, Kolb D, Georgiadi A, Glawitsch L, Heitzer E, Schulz TJ, Schupp M, Sun W, Dong H, Ghosh A, Hoffmann A, Kratky D, Hinte LC, von Meyenn F, Heck AJR, Blüher M, Herzig S, Wolfrum C, Prokesch A. Reinisch I, et al. Among authors: hoffmann a. Nat Commun. 2024 Feb 15;15(1):1391. doi: 10.1038/s41467-024-45724-y. Nat Commun. 2024. PMID: 38360943 Free PMC article.
Apoptotic brown adipocytes enhance energy expenditure via extracellular inosine.
Niemann B, Haufs-Brusberg S, Puetz L, Feickert M, Jaeckstein MY, Hoffmann A, Zurkovic J, Heine M, Trautmann EM, Müller CE, Tönjes A, Schlein C, Jafari A, Eltzschig HK, Gnad T, Blüher M, Krahmer N, Kovacs P, Heeren J, Pfeifer A. Niemann B, et al. Among authors: hoffmann a. Nature. 2022 Sep;609(7926):361-368. doi: 10.1038/s41586-022-05041-0. Epub 2022 Jul 5. Nature. 2022. PMID: 35790189 Free PMC article.
Adipose tissue retains an epigenetic memory of obesity after weight loss.
Hinte LC, Castellano-Castillo D, Ghosh A, Melrose K, Gasser E, Noé F, Massier L, Dong H, Sun W, Hoffmann A, Wolfrum C, Rydén M, Mejhert N, Blüher M, von Meyenn F. Hinte LC, et al. Among authors: hoffmann a. Nature. 2024 Dec;636(8042):457-465. doi: 10.1038/s41586-024-08165-7. Epub 2024 Nov 18. Nature. 2024. PMID: 39558077 Free PMC article.
Intronic tRNAs of mitochondrial origin regulate constitutive and alternative splicing.
Hoser SM, Hoffmann A, Meindl A, Gamper M, Fallmann J, Bernhart SH, Müller L, Ploner M, Misslinger M, Kremser L, Lindner H, Geley S, Schaal H, Stadler PF, Huettenhofer A. Hoser SM, et al. Among authors: hoffmann a. Genome Biol. 2020 Dec 8;21(1):299. doi: 10.1186/s13059-020-02199-6. Genome Biol. 2020. PMID: 33292386 Free PMC article.
2,770 results