Barua B - Search Results

1

Positive cardiac inotrope omecamtiv mecarbil activates muscle despite suppressing the myosin working stroke.

Woody MS, Greenberg MJ, Barua B, Winkelmann DA, Goldman YE, Ostap EM. Woody MS, et al. Among authors: barua b. Nat Commun. 2018 Sep 21;9(1):3838. doi: 10.1038/s41467-018-06193-2. Nat Commun. 2018. PMID: 30242219 Free PMC article.

2

Myosin with hypertrophic cardiac mutation R712L has a decreased working stroke which is rescued by omecamtiv mecarbil.

Snoberger A, Barua B, Atherton JL, Shuman H, Forgacs E, Goldman YE, Winkelmann DA, Ostap EM. Snoberger A, et al. Among authors: barua b. Elife. 2021 Feb 19;10:e63691. doi: 10.7554/eLife.63691. Elife. 2021. PMID: 33605878 Free PMC article.

3

Regulation of actin-myosin interaction by conserved periodic sites of tropomyosin.

Barua B, Winkelmann DA, White HD, Hitchcock-DeGregori SE. Barua B, et al. Proc Natl Acad Sci U S A. 2012 Nov 6;109(45):18425-30. doi: 10.1073/pnas.1212754109. Epub 2012 Oct 22. Proc Natl Acad Sci U S A. 2012. PMID: 23091026 Free PMC article.

4

A periodic pattern of evolutionarily conserved basic and acidic residues constitutes the binding interface of actin-tropomyosin.

Barua B, Fagnant PM, Winkelmann DA, Trybus KM, Hitchcock-DeGregori SE. Barua B, et al. J Biol Chem. 2013 Apr 5;288(14):9602-9609. doi: 10.1074/jbc.M113.451161. Epub 2013 Feb 18. J Biol Chem. 2013. PMID: 23420843 Free PMC article.

5

Regulation of nonmuscle myosin II by tropomyosin.

Barua B, Nagy A, Sellers JR, Hitchcock-DeGregori SE. Barua B, et al. Biochemistry. 2014 Jun 24;53(24):4015-24. doi: 10.1021/bi500162z. Epub 2014 Jun 12. Biochemistry. 2014. PMID: 24873380 Free PMC article.

6

Evolutionarily conserved surface residues constitute actin binding sites of tropomyosin.

Barua B, Pamula MC, Hitchcock-DeGregori SE. Barua B, et al. Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10150-5. doi: 10.1073/pnas.1101221108. Epub 2011 Jun 3. Proc Natl Acad Sci U S A. 2011. PMID: 21642532 Free PMC article.

7

Probing the flexibility of tropomyosin and its binding to filamentous actin using molecular dynamics simulations.

Zheng W, Barua B, Hitchcock-DeGregori SE. Zheng W, et al. Among authors: barua b. Biophys J. 2013 Oct 15;105(8):1882-92. doi: 10.1016/j.bpj.2013.09.003. Biophys J. 2013. PMID: 24138864 Free PMC article.

8

A molecular evolution approach to study the roles of tropomyosin in fission yeast.

Cranz-Mileva S, Pamula MC, Barua B, Desai B, Hong YH, Russell J, Trent R, Wang J, Walworth NC, Hitchcock-DeGregori SE. Cranz-Mileva S, et al. Among authors: barua b. PLoS One. 2013 Oct 22;8(10):e76726. doi: 10.1371/journal.pone.0076726. eCollection 2013. PLoS One. 2013. PMID: 24167549 Free PMC article.

9

Investigating the effects of tropomyosin mutations on its flexibility and interactions with filamentous actin using molecular dynamics simulation.

Zheng W, Hitchcock-DeGregori SE, Barua B. Zheng W, et al. Among authors: barua b. J Muscle Res Cell Motil. 2016 Oct;37(4-5):131-147. doi: 10.1007/s10974-016-9447-3. Epub 2016 Jul 4. J Muscle Res Cell Motil. 2016. PMID: 27376658

10

Distinct sites in tropomyosin specify shared and isoform-specific regulation of myosins II and V.

Barua B, Sckolnick M, White HD, Trybus KM, Hitchcock-DeGregori SE. Barua B, et al. Cytoskeleton (Hoboken). 2018 Apr;75(4):150-163. doi: 10.1002/cm.21440. Epub 2018 Mar 26. Cytoskeleton (Hoboken). 2018. PMID: 29500902 Free PMC article.

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