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Microbiological Analysis from a Phase 2 Randomized Study in Adults Evaluating Single Oral Doses of Gepotidacin in the Treatment of Uncomplicated Urogenital Gonorrhea Caused by Neisseria gonorrhoeae.
Scangarella-Oman NE, Hossain M, Dixon PB, Ingraham K, Min S, Tiffany CA, Perry CR, Raychaudhuri A, Dumont EF, Huang J, Hook EW 3rd, Miller LA. Scangarella-Oman NE, et al. Among authors: tiffany ca. Antimicrob Agents Chemother. 2018 Nov 26;62(12):e01221-18. doi: 10.1128/AAC.01221-18. Print 2018 Dec. Antimicrob Agents Chemother. 2018. PMID: 30249694 Free PMC article. Clinical Trial.
The metabolism and disposition of GSK2140944 in healthy human subjects.
Negash K, Andonian C, Felgate C, Chen C, Goljer I, Squillaci B, Nguyen D, Pirhalla J, Lev M, Schubert E, Tiffany C, Hossain M, Ho M. Negash K, et al. Xenobiotica. 2016 Aug;46(8):683-702. doi: 10.3109/00498254.2015.1112933. Epub 2015 Nov 19. Xenobiotica. 2016. PMID: 26586303
A Phase I, Randomized, Double-Blinded, Placebo- and Moxifloxacin-Controlled, Four-Period Crossover Study To Evaluate the Effect of Gepotidacin on Cardiac Conduction as Assessed by 12-Lead Electrocardiogram in Healthy Volunteers.
Hossain M, Zhou M, Tiffany C, Dumont E, Darpo B. Hossain M, et al. Antimicrob Agents Chemother. 2017 Apr 24;61(5):e02385-16. doi: 10.1128/AAC.02385-16. Print 2017 May. Antimicrob Agents Chemother. 2017. PMID: 28223381 Free PMC article. Clinical Trial.
Efficacy, Safety, and Tolerability of Gepotidacin (GSK2140944) in the Treatment of Patients with Suspected or Confirmed Gram-Positive Acute Bacterial Skin and Skin Structure Infections.
O'Riordan W, Tiffany C, Scangarella-Oman N, Perry C, Hossain M, Ashton T, Dumont E. O'Riordan W, et al. Antimicrob Agents Chemother. 2017 May 24;61(6):e02095-16. doi: 10.1128/AAC.02095-16. Print 2017 Jun. Antimicrob Agents Chemother. 2017. PMID: 28373199 Free PMC article. Clinical Trial.
Gepotidacin for the Treatment of Uncomplicated Urogenital Gonorrhea: A Phase 2, Randomized, Dose-Ranging, Single-Oral Dose Evaluation.
Taylor SN, Morris DH, Avery AK, Workowski KA, Batteiger BE, Tiffany CA, Perry CR, Raychaudhuri A, Scangarella-Oman NE, Hossain M, Dumont EF. Taylor SN, et al. Among authors: tiffany ca. Clin Infect Dis. 2018 Aug 1;67(4):504-512. doi: 10.1093/cid/ciy145. Clin Infect Dis. 2018. PMID: 29617982 Free PMC article. Clinical Trial.
In Vitro Activity and Microbiological Efficacy of Gepotidacin from a Phase 2, Randomized, Multicenter, Dose-Ranging Study in Patients with Acute Bacterial Skin and Skin Structure Infections.
Scangarella-Oman NE, Ingraham KA, Tiffany CA, Tomsho L, Van Horn SF, Mayhew DN, Perry CR, Ashton TC, Dumont EF, Huang J, Brown JR, Miller LA. Scangarella-Oman NE, et al. Among authors: tiffany ca. Antimicrob Agents Chemother. 2020 Feb 21;64(3):e01302-19. doi: 10.1128/AAC.01302-19. Print 2020 Feb 21. Antimicrob Agents Chemother. 2020. PMID: 31818823 Free PMC article.
Phase 2a Pharmacokinetic, Safety, and Exploratory Efficacy Evaluation of Oral Gepotidacin (GSK2140944) in Female Participants with Uncomplicated Urinary Tract Infection (Acute Uncomplicated Cystitis).
Overcash JS, Tiffany CA, Scangarella-Oman NE, Perry CR, Tao Y, Hossain M, Barth A, Dumont EF. Overcash JS, et al. Among authors: tiffany ca. Antimicrob Agents Chemother. 2020 Jun 23;64(7):e00199-20. doi: 10.1128/AAC.00199-20. Print 2020 Jun 23. Antimicrob Agents Chemother. 2020. PMID: 32284384 Free PMC article. Clinical Trial.
Pharmacokinetics of Gepotidacin in Renal Impairment.
Hossain M, Tiffany C, Raychaudhuri A, Nguyen D, Tai G, Alcorn H Jr, Preston RA, Marbury T, Dumont E. Hossain M, et al. Clin Pharmacol Drug Dev. 2020 Jul;9(5):560-572. doi: 10.1002/cpdd.807. Epub 2020 May 19. Clin Pharmacol Drug Dev. 2020. PMID: 32429000 Free PMC article. Clinical Trial.
16 results