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Use of an in vitro pharmacodynamic model to derive a linezolid regimen that optimizes bacterial kill and prevents emergence of resistance in Bacillus anthracis.
Louie A, Heine HS, Kim K, Brown DL, VanScoy B, Liu W, Kinzig-Schippers M, Sörgel F, Drusano GL. Louie A, et al. Among authors: brown dl. Antimicrob Agents Chemother. 2008 Jul;52(7):2486-96. doi: 10.1128/AAC.01439-07. Epub 2008 May 5. Antimicrob Agents Chemother. 2008. PMID: 18458134 Free PMC article.
Impact of different carbapenems and regimens of administration on resistance emergence for three isogenic Pseudomonas aeruginosa strains with differing mechanisms of resistance.
Louie A, Bied A, Fregeau C, Van Scoy B, Brown D, Liu W, Bush K, Queenan AM, Morrow B, Khashab M, Kahn JB, Nicholson S, Kulawy R, Drusano GL. Louie A, et al. Among authors: brown d. Antimicrob Agents Chemother. 2010 Jun;54(6):2638-45. doi: 10.1128/AAC.01721-09. Epub 2010 Mar 22. Antimicrob Agents Chemother. 2010. PMID: 20308371 Free PMC article.
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