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Prelamin A causes aberrant myonuclear arrangement and results in muscle fiber weakness.
Levy Y, Ross JA, Niglas M, Snetkov VA, Lynham S, Liao CY, Puckelwartz MJ, Hsu YM, McNally EM, Alsheimer M, Harridge SD, Young SG, Fong LG, Español Y, Lopez-Otin C, Kennedy BK, Lowe DA, Ochala J. Levy Y, et al. JCI Insight. 2018 Oct 4;3(19):e120920. doi: 10.1172/jci.insight.120920. JCI Insight. 2018. PMID: 30282816 Free PMC article.
Comparative genomics of mortal and immortal cnidarians unveils novel keys behind rejuvenation.
Pascual-Torner M, Carrero D, Pérez-Silva JG, Álvarez-Puente D, Roiz-Valle D, Bretones G, Rodríguez D, Maeso D, Mateo-González E, Español Y, Mariño G, Acuña JL, Quesada V, López-Otín C. Pascual-Torner M, et al. Proc Natl Acad Sci U S A. 2022 Sep 6;119(36):e2118763119. doi: 10.1073/pnas.2118763119. Epub 2022 Aug 29. Proc Natl Acad Sci U S A. 2022. PMID: 36037356 Free PMC article.
Autophagy-linked plasma and lysosomal membrane protein PLAC8 is a key host factor for SARS-CoV-2 entry into human cells.
Ugalde AP, Bretones G, Rodríguez D, Quesada V, Llorente F, Fernández-Delgado R, Jiménez-Clavero MÁ, Vázquez J, Calvo E, Tamargo-Gómez I, Mariño G, Roiz-Valle D, Maeso D, Araujo-Voces M, Español Y, Barceló C, Freije JM, López-Soto A, López-Otín C. Ugalde AP, et al. EMBO J. 2022 Nov 2;41(21):e110727. doi: 10.15252/embj.2022110727. Epub 2022 Oct 4. EMBO J. 2022. PMID: 36124427 Free PMC article.
Nuclear envelope defects cause stem cell dysfunction in premature-aging mice.
Espada J, Varela I, Flores I, Ugalde AP, Cadiñanos J, Pendás AM, Stewart CL, Tryggvason K, Blasco MA, Freije JM, López-Otín C. Espada J, et al. J Cell Biol. 2008 Apr 7;181(1):27-35. doi: 10.1083/jcb.200801096. Epub 2008 Mar 31. J Cell Biol. 2008. PMID: 18378773 Free PMC article.
547 results