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Adolescent exposure to Δ9-tetrahydrocannabinol alters the transcriptional trajectory and dendritic architecture of prefrontal pyramidal neurons.
Miller ML, Chadwick B, Dickstein DL, Purushothaman I, Egervari G, Rahman T, Tessereau C, Hof PR, Roussos P, Shen L, Baxter MG, Hurd YL. Miller ML, et al. Among authors: purushothaman i. Mol Psychiatry. 2019 Apr;24(4):588-600. doi: 10.1038/s41380-018-0243-x. Epub 2018 Oct 3. Mol Psychiatry. 2019. PMID: 30283037 Free PMC article.
Ketamine and Imipramine Reverse Transcriptional Signatures of Susceptibility and Induce Resilience-Specific Gene Expression Profiles.
Bagot RC, Cates HM, Purushothaman I, Vialou V, Heller EA, Yieh L, LaBonté B, Peña CJ, Shen L, Wittenberg GM, Nestler EJ. Bagot RC, et al. Among authors: purushothaman i. Biol Psychiatry. 2017 Feb 15;81(4):285-295. doi: 10.1016/j.biopsych.2016.06.012. Epub 2016 Jun 18. Biol Psychiatry. 2017. PMID: 27569543 Free PMC article.
A novel role for E2F3b in regulating cocaine action in the prefrontal cortex.
Cates HM, Bagot RC, Heller EA, Purushothaman I, Lardner CK, Walker DM, Peña CJ, Neve RL, Shen L, Nestler EJ. Cates HM, et al. Among authors: purushothaman i. Neuropsychopharmacology. 2019 Mar;44(4):776-784. doi: 10.1038/s41386-018-0296-1. Epub 2018 Dec 14. Neuropsychopharmacology. 2019. PMID: 30552390 Free PMC article.
Critical Role of Histone Turnover in Neuronal Transcription and Plasticity.
Maze I, Wenderski W, Noh KM, Bagot RC, Tzavaras N, Purushothaman I, Elsässer SJ, Guo Y, Ionete C, Hurd YL, Tamminga CA, Halene T, Farrelly L, Soshnev AA, Wen D, Rafii S, Birtwistle MR, Akbarian S, Buchholz BA, Blitzer RD, Nestler EJ, Yuan ZF, Garcia BA, Shen L, Molina H, Allis CD. Maze I, et al. Among authors: purushothaman i. Neuron. 2015 Jul 1;87(1):77-94. doi: 10.1016/j.neuron.2015.06.014. Neuron. 2015. PMID: 26139371 Free PMC article.
Cocaine Self-administration Alters Transcriptome-wide Responses in the Brain's Reward Circuitry.
Walker DM, Cates HM, Loh YE, Purushothaman I, Ramakrishnan A, Cahill KM, Lardner CK, Godino A, Kronman HG, Rabkin J, Lorsch ZS, Mews P, Doyle MA, Feng J, Labonté B, Koo JW, Bagot RC, Logan RW, Seney ML, Calipari ES, Shen L, Nestler EJ. Walker DM, et al. Among authors: purushothaman i. Biol Psychiatry. 2018 Dec 15;84(12):867-880. doi: 10.1016/j.biopsych.2018.04.009. Epub 2018 Apr 25. Biol Psychiatry. 2018. PMID: 29861096 Free PMC article.
Sex-specific transcriptional signatures in human depression.
Labonté B, Engmann O, Purushothaman I, Menard C, Wang J, Tan C, Scarpa JR, Moy G, Loh YE, Cahill M, Lorsch ZS, Hamilton PJ, Calipari ES, Hodes GE, Issler O, Kronman H, Pfau M, Obradovic ALJ, Dong Y, Neve RL, Russo S, Kazarskis A, Tamminga C, Mechawar N, Turecki G, Zhang B, Shen L, Nestler EJ. Labonté B, et al. Among authors: purushothaman i. Nat Med. 2017 Sep;23(9):1102-1111. doi: 10.1038/nm.4386. Epub 2017 Aug 21. Nat Med. 2017. PMID: 28825715 Free PMC article.
41 results