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Synthesis, in vitro and in vivo biological evaluation, COX-1/2 inhibition and molecular docking study of indole-N-acylhydrazone derivatives.
Moraes ADTO, Miranda MDS, Jacob ÍTT, Amorim CADC, Moura RO, Silva SÂSD, Soares MBP, Almeida SMV, Souza TRCL, Oliveira JF, Silva TGD, Melo CML, Moreira DRM, Lima MDCA. Moraes ADTO, et al. Among authors: amorim cadc. Bioorg Med Chem. 2018 Nov 1;26(20):5388-5396. doi: 10.1016/j.bmc.2018.07.024. Epub 2018 Jul 17. Bioorg Med Chem. 2018. PMID: 30293795
Synthesis of novel indole derivatives as promising DNA-binding agents and evaluation of antitumor and antitopoisomerase I activities.
Lafayette EA, de Almeida SMV, Cavalcanti Santos RV, de Oliveira JF, Amorim CADC, da Silva RMF, Pitta MGDR, Pitta IDR, de Moura RO, de Carvalho Júnior LB, de Melo Rêgo MJB, de Lima MDCA. Lafayette EA, et al. Among authors: amorim cadc. Eur J Med Chem. 2017 Aug 18;136:511-522. doi: 10.1016/j.ejmech.2017.05.012. Epub 2017 May 4. Eur J Med Chem. 2017. PMID: 28531811