Wang HR - Search Results

1

ATR/Chk1 signaling induces autophagy through sumoylated RhoB-mediated lysosomal translocation of TSC2 after DNA damage.

Liu M, Zeng T, Zhang X, Liu C, Wu Z, Yao L, Xie C, Xia H, Lin Q, Xie L, Zhou D, Deng X, Chan HL, Zhao TJ, Wang HR. Liu M, et al. Among authors: wang hr. Nat Commun. 2018 Oct 8;9(1):4139. doi: 10.1038/s41467-018-06556-9. Nat Commun. 2018. PMID: 30297842 Free PMC article.

2

Binding of RhoA by the C2 domain of E3 ligase Smurf1 is essential for Smurf1-regulated RhoA ubiquitination and cell protrusive activity.

Tian M, Bai C, Lin Q, Lin H, Liu M, Ding F, Wang HR. Tian M, et al. Among authors: wang hr. FEBS Lett. 2011 Jul 21;585(14):2199-204. doi: 10.1016/j.febslet.2011.06.016. Epub 2011 Jun 23. FEBS Lett. 2011. PMID: 21708152 Free article.

3

Impeded Nedd4-1-mediated Ras degradation underlies Ras-driven tumorigenesis.

Zeng T, Wang Q, Fu J, Lin Q, Bi J, Ding W, Qiao Y, Zhang S, Zhao W, Lin H, Wang M, Lu B, Deng X, Zhou D, Yin Z, Wang HR. Zeng T, et al. Among authors: wang m, wang hr, wang q. Cell Rep. 2014 May 8;7(3):871-82. doi: 10.1016/j.celrep.2014.03.045. Epub 2014 Apr 17. Cell Rep. 2014. PMID: 24746824 Free article.

4

ATR/Chk1/Smurf1 pathway determines cell fate after DNA damage by controlling RhoB abundance.

Wang M, Guo L, Wu Q, Zeng T, Lin Q, Qiao Y, Wang Q, Liu M, Zhang X, Ren L, Zhang S, Pei Y, Yin Z, Ding F, Wang HR. Wang M, et al. Among authors: wang hr, wang q. Nat Commun. 2014 Sep 24;5:4901. doi: 10.1038/ncomms5901. Nat Commun. 2014. PMID: 25249323 Free article.

5

Integration of Hippo signalling and the unfolded protein response to restrain liver overgrowth and tumorigenesis.

Wu H, Wei L, Fan F, Ji S, Zhang S, Geng J, Hong L, Fan X, Chen Q, Tian J, Jiang M, Sun X, Jin C, Yin ZY, Liu Q, Zhang J, Qin F, Lin KH, Yu JS, Deng X, Wang HR, Zhao B, Johnson RL, Chen L, Zhou D. Wu H, et al. Among authors: wang hr. Nat Commun. 2015 Feb 19;6:6239. doi: 10.1038/ncomms7239. Nat Commun. 2015. PMID: 25695629 Free article.

6

Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity.

Geng J, Sun X, Wang P, Zhang S, Wang X, Wu H, Hong L, Xie C, Li X, Zhao H, Liu Q, Jiang M, Chen Q, Zhang J, Li Y, Song S, Wang HR, Zhou R, Johnson RL, Chien KY, Lin SC, Han J, Avruch J, Chen L, Zhou D. Geng J, et al. Among authors: wang x, wang p, wang hr. Nat Immunol. 2015 Nov;16(11):1142-52. doi: 10.1038/ni.3268. Epub 2015 Sep 28. Nat Immunol. 2015. PMID: 26414765 Free PMC article.

7

Targeting BRK-Positive Breast Cancers with Small-Molecule Kinase Inhibitors.

Jiang J, Gui F, He Z, Li L, Li Y, Li S, Wu X, Deng Z, Sun X, Huang X, Huang W, Han S, Zhang T, Wang Z, Jiao B, Song S, Wang H, Chen L, Zhou D, Liu Q, Ren R, Zhang J, Deng X. Jiang J, et al. Cancer Res. 2017 Jan 1;77(1):175-186. doi: 10.1158/0008-5472.CAN-16-1038. Epub 2016 Oct 10. Cancer Res. 2017. PMID: 27758886

8

A cell-based high-throughput screening method based on a ubiquitin-reference technique for identifying modulators of E3 ligases.

Tian M, Zeng T, Liu M, Han S, Lin H, Lin Q, Li L, Jiang T, Li G, Lin H, Zhang T, Kang Q, Deng X, Wang HR. Tian M, et al. Among authors: wang hr. J Biol Chem. 2019 Feb 22;294(8):2880-2891. doi: 10.1074/jbc.RA118.003822. Epub 2018 Dec 26. J Biol Chem. 2019. PMID: 30587574 Free PMC article.

9

DHHC4 and DHHC5 Facilitate Fatty Acid Uptake by Palmitoylating and Targeting CD36 to the Plasma Membrane.

Wang J, Hao JW, Wang X, Guo H, Sun HH, Lai XY, Liu LY, Zhu M, Wang HY, Li YF, Yu LY, Xie C, Wang HR, Mo W, Zhou HM, Chen S, Liang G, Zhao TJ. Wang J, et al. Among authors: wang x, wang hy, wang hr. Cell Rep. 2019 Jan 2;26(1):209-221.e5. doi: 10.1016/j.celrep.2018.12.022. Cell Rep. 2019. PMID: 30605677 Free article.

10

Monoubiquitination of p120-catenin is essential for TGFβ-induced epithelial-mesenchymal transition and tumor metastasis.

Wu Q, Li G, Wen C, Zeng T, Fan Y, Liu C, Fu GF, Xie C, Lin Q, Xie L, Huang L, Pu P, Ouyang Z, Chan HL, Zhao TJ, Chen XL, Fu G, Wang HR. Wu Q, et al. Among authors: wang hr. Sci Adv. 2020 Jan 22;6(4):eaay9819. doi: 10.1126/sciadv.aay9819. eCollection 2020 Jan. Sci Adv. 2020. PMID: 32010791 Free PMC article.

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