McCann JL - Search Results

1

Genetic and mechanistic basis for APOBEC3H alternative splicing, retrovirus restriction, and counteraction by HIV-1 protease.

Ebrahimi D, Richards CM, Carpenter MA, Wang J, Ikeda T, Becker JT, Cheng AZ, McCann JL, Shaban NM, Salamango DJ, Starrett GJ, Lingappa JR, Yong J, Brown WL, Harris RS. Ebrahimi D, et al. Among authors: mccann jl. Nat Commun. 2018 Oct 8;9(1):4137. doi: 10.1038/s41467-018-06594-3. Nat Commun. 2018. PMID: 30297863 Free PMC article.

2

The PKC/NF-κB signaling pathway induces APOBEC3B expression in multiple human cancers.

Leonard B, McCann JL, Starrett GJ, Kosyakovsky L, Luengas EM, Molan AM, Burns MB, McDougle RM, Parker PJ, Brown WL, Harris RS. Leonard B, et al. Among authors: mccann jl. Cancer Res. 2015 Nov 1;75(21):4538-47. doi: 10.1158/0008-5472.CAN-15-2171-T. Epub 2015 Sep 29. Cancer Res. 2015. PMID: 26420215 Free PMC article.

3

The DNA cytosine deaminase APOBEC3H haplotype I likely contributes to breast and lung cancer mutagenesis.

Starrett GJ, Luengas EM, McCann JL, Ebrahimi D, Temiz NA, Love RP, Feng Y, Adolph MB, Chelico L, Law EK, Carpenter MA, Harris RS. Starrett GJ, et al. Among authors: mccann jl. Nat Commun. 2016 Sep 21;7:12918. doi: 10.1038/ncomms12918. Nat Commun. 2016. PMID: 27650891 Free PMC article.

4

Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B.

Shi K, Carpenter MA, Banerjee S, Shaban NM, Kurahashi K, Salamango DJ, McCann JL, Starrett GJ, Duffy JV, Demir Ö, Amaro RE, Harki DA, Harris RS, Aihara H. Shi K, et al. Among authors: mccann jl. Nat Struct Mol Biol. 2017 Feb;24(2):131-139. doi: 10.1038/nsmb.3344. Epub 2016 Dec 19. Nat Struct Mol Biol. 2017. PMID: 27991903 Free PMC article.

5

APOBEC3B Nuclear Localization Requires Two Distinct N-Terminal Domain Surfaces.

Salamango DJ, McCann JL, Demir Ö, Brown WL, Amaro RE, Harris RS. Salamango DJ, et al. Among authors: mccann jl. J Mol Biol. 2018 Aug 17;430(17):2695-2708. doi: 10.1016/j.jmb.2018.04.044. Epub 2018 May 19. J Mol Biol. 2018. PMID: 29787764 Free PMC article.

6

APOBEC3H Subcellular Localization Determinants Define Zipcode for Targeting HIV-1 for Restriction.

Salamango DJ, Becker JT, McCann JL, Cheng AZ, Demir Ö, Amaro RE, Brown WL, Shaban NM, Harris RS. Salamango DJ, et al. Among authors: mccann jl. Mol Cell Biol. 2018 Nov 13;38(23):e00356-18. doi: 10.1128/MCB.00356-18. Print 2018 Dec 1. Mol Cell Biol. 2018. PMID: 30224517 Free PMC article.

7

Epstein-Barr virus BORF2 inhibits cellular APOBEC3B to preserve viral genome integrity.

Cheng AZ, Yockteng-Melgar J, Jarvis MC, Malik-Soni N, Borozan I, Carpenter MA, McCann JL, Ebrahimi D, Shaban NM, Marcon E, Greenblatt J, Brown WL, Frappier L, Harris RS. Cheng AZ, et al. Among authors: mccann jl. Nat Microbiol. 2019 Jan;4(1):78-88. doi: 10.1038/s41564-018-0284-6. Epub 2018 Nov 12. Nat Microbiol. 2019. PMID: 30420783 Free PMC article.

8

Polyomavirus T Antigen Induces APOBEC3B Expression Using an LXCXE-Dependent and TP53-Independent Mechanism.

Starrett GJ, Serebrenik AA, Roelofs PA, McCann JL, Verhalen B, Jarvis MC, Stewart TA, Law EK, Krupp A, Jiang M, Martens JWM, Cahir-McFarland E, Span PN, Harris RS. Starrett GJ, et al. Among authors: mccann jl. mBio. 2019 Feb 5;10(1):e02690-18. doi: 10.1128/mBio.02690-18. mBio. 2019. PMID: 30723127 Free PMC article.

9

The DNA deaminase APOBEC3B interacts with the cell-cycle protein CDK4 and disrupts CDK4-mediated nuclear import of Cyclin D1.

McCann JL, Klein MM, Leland EM, Law EK, Brown WL, Salamango DJ, Harris RS. McCann JL, et al. J Biol Chem. 2019 Aug 9;294(32):12099-12111. doi: 10.1074/jbc.RA119.008443. Epub 2019 Jun 19. J Biol Chem. 2019. PMID: 31217276 Free PMC article.

10

HIV-1 Vif Triggers Cell Cycle Arrest by Degrading Cellular PPP2R5 Phospho-regulators.

Salamango DJ, Ikeda T, Moghadasi SA, Wang J, McCann JL, Serebrenik AA, Ebrahimi D, Jarvis MC, Brown WL, Harris RS. Salamango DJ, et al. Among authors: mccann jl. Cell Rep. 2019 Oct 29;29(5):1057-1065.e4. doi: 10.1016/j.celrep.2019.09.057. Cell Rep. 2019. PMID: 31665623 Free PMC article.

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