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14 results

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Safety, efficacy, and dose response of the maturation inhibitor GSK3532795 (formerly known as BMS-955176) plus tenofovir/emtricitabine once daily in treatment-naive HIV-1-infected adults: Week 24 primary analysis from a randomized Phase IIb trial.
Morales-Ramirez J, Bogner JR, Molina JM, Lombaard J, Dicker IB, Stock DA, DeGrosky M, Gartland M, Pene Dumitrescu T, Min S, Llamoso C, Joshi SR, Lataillade M. Morales-Ramirez J, et al. Among authors: pene dumitrescu t. PLoS One. 2018 Oct 23;13(10):e0205368. doi: 10.1371/journal.pone.0205368. eCollection 2018. PLoS One. 2018. PMID: 30352054 Free PMC article. Clinical Trial.
A Phase I Evaluation of the Pharmacokinetics and Tolerability of the HIV-1 Maturation Inhibitor GSK3640254 and Tenofovir Alafenamide/Emtricitabine in Healthy Participants.
Pene Dumitrescu T, Joshi SR, Xu J, Zhan J, Johnson M, Butcher L, Zimmerman E, Webster L, Davidson AM, Lataillade M, Min S. Pene Dumitrescu T, et al. Antimicrob Agents Chemother. 2021 May 18;65(6):e02173-20. doi: 10.1128/AAC.02173-20. Print 2021 May 18. Antimicrob Agents Chemother. 2021. PMID: 33753329 Free PMC article. Clinical Trial.
A phase 2a randomized controlled study to evaluate the pharmacokinetic, safety, tolerability and clinical effect of topically applied Umeclidinium in subjects with primary axillary hyperhidrosis.
Nasir A, Bissonnette R, Maari C, DuBois J, Pene Dumitrescu T, Haddad J, Yamaguchi Y, Dalessandro M. Nasir A, et al. Among authors: pene dumitrescu t. J Eur Acad Dermatol Venereol. 2018 Jan;32(1):145-151. doi: 10.1111/jdv.14651. Epub 2017 Nov 7. J Eur Acad Dermatol Venereol. 2018. PMID: 29055158 Clinical Trial.
A Novel Method for Studying the Pharmacokinetics of [(14) C]Umeclidinium After Application to the Axilla or Palm of Healthy Male Subjects.
Pene Dumitrescu T, Santos LL, Hughes SC, Pereira AI, Young GC, Hussey E, Charlton P, Baptiste-Brown S, Stuart JS, Vincent V, van Marle SP, Schmith VD. Pene Dumitrescu T, et al. Clin Transl Sci. 2016 Aug;9(4):183-91. doi: 10.1111/cts.12406. Epub 2016 Jun 15. Clin Transl Sci. 2016. PMID: 27304394 Free PMC article. Clinical Trial.
Phase I Study of the Novel Enhancer of Zeste Homolog 2 (EZH2) Inhibitor GSK2816126 in Patients with Advanced Hematologic and Solid Tumors.
Yap TA, Winter JN, Giulino-Roth L, Longley J, Lopez J, Michot JM, Leonard JP, Ribrag V, McCabe MT, Creasy CL, Stern M, Pene Dumitrescu T, Wang X, Frey S, Carver J, Horner T, Oh C, Khaled A, Dhar A, Johnson PWM. Yap TA, et al. Among authors: pene dumitrescu t. Clin Cancer Res. 2019 Dec 15;25(24):7331-7339. doi: 10.1158/1078-0432.CCR-18-4121. Epub 2019 Aug 30. Clin Cancer Res. 2019. PMID: 31471312 Free PMC article. Clinical Trial.
Population pharmacokinetic modeling of dolutegravir/lamivudine to support a once-daily fixed-dose combination regimen in virologically suppressed adults living with HIV-1.
Chandasana H, Singh R, Adkison K, Ait-Khaled M, Pene Dumitrescu T. Chandasana H, et al. Among authors: pene dumitrescu t. Antimicrob Agents Chemother. 2024 May 2;68(5):e0150423. doi: 10.1128/aac.01504-23. Epub 2024 Apr 8. Antimicrob Agents Chemother. 2024. PMID: 38587380 Free PMC article. Clinical Trial.
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