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Page 1
Loss of EMILIN-1 Enhances Arteriolar Myogenic Tone Through TGF-β (Transforming Growth Factor-β)-Dependent Transactivation of EGFR (Epidermal Growth Factor Receptor) and Is Relevant for Hypertension in Mice and Humans.
Carnevale D, Facchinello N, Iodice D, Bizzotto D, Perrotta M, De Stefani D, Pallante F, Carnevale L, Ricciardi F, Cifelli G, Da Ros F, Casaburo M, Fardella S, Bonaldo P, Innocenzi G, Rizzuto R, Braghetta P, Lembo G, Bressan GM. Carnevale D, et al. Among authors: cifelli g. Arterioscler Thromb Vasc Biol. 2018 Oct;38(10):2484-2497. doi: 10.1161/ATVBAHA.118.311115. Arterioscler Thromb Vasc Biol. 2018. PMID: 30354220
Vascular smooth muscle Emilin-1 is a regulator of arteriolar myogenic response and blood pressure.
Litteri G, Carnevale D, D'Urso A, Cifelli G, Braghetta P, Damato A, Bizzotto D, Landolfi A, Ros FD, Sabatelli P, Facchinello N, Maffei A, Volpin D, Colombatti A, Bressan GM, Lembo G. Litteri G, et al. Among authors: cifelli g. Arterioscler Thromb Vasc Biol. 2012 Sep;32(9):2178-84. doi: 10.1161/ATVBAHA.112.254664. Epub 2012 Jul 19. Arterioscler Thromb Vasc Biol. 2012. PMID: 22814752
Targeting Interleukin-1β Protects from Aortic Aneurysms Induced by Disrupted Transforming Growth Factor β Signaling.
Da Ros F, Carnevale R, Cifelli G, Bizzotto D, Casaburo M, Perrotta M, Carnevale L, Vinciguerra I, Fardella S, Iacobucci R, Bressan GM, Braghetta P, Lembo G, Carnevale D. Da Ros F, et al. Among authors: cifelli g. Immunity. 2017 Nov 21;47(5):959-973.e9. doi: 10.1016/j.immuni.2017.10.016. Epub 2017 Nov 14. Immunity. 2017. PMID: 29150241 Free article.
PI3Kγ Inhibition Protects Against Diabetic Cardiomyopathy in Mice.
Maffei A, Cifelli G, Carnevale R, Iacobucci R, Pallante F, Fardella V, Fardella S, Hirsch E, Lembo G, Carnevale D. Maffei A, et al. Among authors: cifelli g. Rev Esp Cardiol (Engl Ed). 2017 Jan;70(1):16-24. doi: 10.1016/j.rec.2016.04.034. Epub 2016 Jul 13. Rev Esp Cardiol (Engl Ed). 2017. PMID: 27422446 English, Spanish.
PI3Kγ inhibition reduces blood pressure by a vasorelaxant Akt/L-type calcium channel mechanism.
Carnevale D, Vecchione C, Mascio G, Esposito G, Cifelli G, Martinello K, Landolfi A, Selvetella G, Grieco P, Damato A, Franco E, Haase H, Maffei A, Ciraolo E, Fucile S, Frati G, Mazzoni O, Hirsch E, Lembo G. Carnevale D, et al. Among authors: cifelli g. Cardiovasc Res. 2012 Jan 1;93(1):200-9. doi: 10.1093/cvr/cvr288. Epub 2011 Oct 27. Cardiovasc Res. 2012. PMID: 22038741
Placental growth factor regulates cardiac inflammation through the tissue inhibitor of metalloproteinases-3/tumor necrosis factor-α-converting enzyme axis: crucial role for adaptive cardiac remodeling during cardiac pressure overload.
Carnevale D, Cifelli G, Mascio G, Madonna M, Sbroggiò M, Perrino C, Persico MG, Frati G, Lembo G. Carnevale D, et al. Among authors: cifelli g. Circulation. 2011 Sep 20;124(12):1337-50. doi: 10.1161/CIRCULATIONAHA.111.050500. Epub 2011 Sep 6. Circulation. 2011. PMID: 21900081
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