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pRAD50: a novel and clinically applicable pharmacodynamic biomarker of both ATM and ATR inhibition identified using mass spectrometry and immunohistochemistry.
Br J Cancer. 2018 Nov;119(10):1233-1243. doi: 10.1038/s41416-018-0286-4. Epub 2018 Nov 2.
Br J Cancer. 2018.
PMID: 30385821
Free PMC article.
Orally Bioavailable and Blood-Brain Barrier-Penetrating ATM Inhibitor (AZ32) Radiosensitizes Intracranial Gliomas in Mice.
Karlin J, Allen J, Ahmad SF, Hughes G, Sheridan V, Odedra R, Farrington P, Cadogan EB, Riches LC, Garcia-Trinidad A, Thomason AG, Patel B, Vincent J, Lau A, Pike KG, Hunt TA, Sule A, Valerie NCK, Biddlestone-Thorpe L, Kahn J, Beckta JM, Mukhopadhyay N, Barlaam B, Degorce SL, Kettle J, Colclough N, Wilson J, Smith A, Barrett IP, Zheng L, Zhang T, Wang Y, Chen K, Pass M, Durant ST, Valerie K.
Karlin J, et al. Among authors: garcia trinidad a.
Mol Cancer Ther. 2018 Aug;17(8):1637-1647. doi: 10.1158/1535-7163.MCT-17-0975. Epub 2018 May 16.
Mol Cancer Ther. 2018.
PMID: 29769307
Free PMC article.
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Phosphatidylcholine-specific phospholipase C activity is necessary for the activation of STAT6.
Zamorano J, Rivas MD, Garcia-Trinidad A, Qu CK, Keegan AD.
Zamorano J, et al. Among authors: garcia trinidad a.
J Immunol. 2003 Oct 15;171(8):4203-9. doi: 10.4049/jimmunol.171.8.4203.
J Immunol. 2003.
PMID: 14530343
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