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The γδTCR combines innate immunity with adaptive immunity by utilizing spatially distinct regions for agonist selection and antigen responsiveness.
Melandri D, Zlatareva I, Chaleil RAG, Dart RJ, Chancellor A, Nussbaumer O, Polyakova O, Roberts NA, Wesch D, Kabelitz D, Irving PM, John S, Mansour S, Bates PA, Vantourout P, Hayday AC. Melandri D, et al. Among authors: roberts na. Nat Immunol. 2018 Dec;19(12):1352-1365. doi: 10.1038/s41590-018-0253-5. Epub 2018 Nov 12. Nat Immunol. 2018. PMID: 30420626 Free PMC article.
Epithelia Use Butyrophilin-like Molecules to Shape Organ-Specific γδ T Cell Compartments.
Di Marco Barros R, Roberts NA, Dart RJ, Vantourout P, Jandke A, Nussbaumer O, Deban L, Cipolat S, Hart R, Iannitto ML, Laing A, Spencer-Dene B, East P, Gibbons D, Irving PM, Pereira P, Steinhoff U, Hayday A. Di Marco Barros R, et al. Among authors: roberts na. Cell. 2016 Sep 22;167(1):203-218.e17. doi: 10.1016/j.cell.2016.08.030. Epub 2016 Sep 15. Cell. 2016. PMID: 27641500 Free PMC article.
Rank signaling links the development of invariant γδ T cell progenitors and Aire(+) medullary epithelium.
Roberts NA, White AJ, Jenkinson WE, Turchinovich G, Nakamura K, Withers DR, McConnell FM, Desanti GE, Benezech C, Parnell SM, Cunningham AF, Paolino M, Penninger JM, Simon AK, Nitta T, Ohigashi I, Takahama Y, Caamano JH, Hayday AC, Lane PJ, Jenkinson EJ, Anderson G. Roberts NA, et al. Immunity. 2012 Mar 23;36(3):427-37. doi: 10.1016/j.immuni.2012.01.016. Epub 2012 Mar 15. Immunity. 2012. PMID: 22425250 Free PMC article.
Prdm1 Regulates Thymic Epithelial Function To Prevent Autoimmunity.
Roberts NA, Adams BD, McCarthy NI, Tooze RM, Parnell SM, Anderson G, Kaech SM, Horsley V. Roberts NA, et al. J Immunol. 2017 Aug 15;199(4):1250-1260. doi: 10.4049/jimmunol.1600941. Epub 2017 Jul 12. J Immunol. 2017. PMID: 28701508 Free PMC article.
Tumor- and host-derived heparanase-2 (Hpa2) attenuates tumorigenicity: role of Hpa2 in macrophage polarization and BRD7 nuclear localization.
Soboh S, Vorontsova A, Farhoud M, Barash U, Naroditsky I, Gross-Cohen M, Weissmann M, Yasuhiko N, Woolf AS, Roberts NA, Shaked Y, Ilan N, Vlodavsky I. Soboh S, et al. Among authors: roberts na. Cell Death Dis. 2024 Dec 18;15(12):894. doi: 10.1038/s41419-024-07262-9. Cell Death Dis. 2024. PMID: 39695102 Free PMC article.
157 results