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Evaluation of the methoxy-X04 derivative BSC4090 for diagnosis of prodromal and early Alzheimer's disease from bioptic olfactory mucosa.
Pellkofer H, Ihler F, Weiss BG, Trothe J, Kadavath H, Chongtham M, Kunadt M, Riedel D, Lornsen F, Wilken P, Bartels C, Hirschel S, Russo SG, Stransky E, Trojan L, Schmidt B, Mandelkow E, Zweckstetter M, Canis M, Schneider A. Pellkofer H, et al. Among authors: mandelkow e. Eur Arch Psychiatry Clin Neurosci. 2019 Dec;269(8):973-984. doi: 10.1007/s00406-018-0955-6. Epub 2018 Nov 12. Eur Arch Psychiatry Clin Neurosci. 2019. PMID: 30421149
Plasma extracellular vesicle tau and TDP-43 as diagnostic biomarkers in FTD and ALS.
Chatterjee M, Özdemir S, Fritz C, Möbius W, Kleineidam L, Mandelkow E, Biernat J, Doğdu C, Peters O, Cosma NC, Wang X, Schneider LS, Priller J, Spruth E, Kühn AA, Krause P, Klockgether T, Vogt IR, Kimmich O, Spottke A, Hoffmann DC, Fliessbach K, Miklitz C, McCormick C, Weydt P, Falkenburger B, Brandt M, Guenther R, Dinter E, Wiltfang J, Hansen N, Bähr M, Zerr I, Flöel A, Nestor PJ, Düzel E, Glanz W, Incesoy E, Bürger K, Janowitz D, Perneczky R, Rauchmann BS, Hopfner F, Wagemann O, Levin J, Teipel S, Kilimann I, Goerss D, Prudlo J, Gasser T, Brockmann K, Mengel D, Zimmermann M, Synofzik M, Wilke C, Selma-González J, Turon-Sans J, Santos-Santos MA, Alcolea D, Rubio-Guerra S, Fortea J, Carbayo Á, Lleó A, Rojas-García R, Illán-Gala I, Wagner M, Frommann I, Roeske S, Bertram L, Heneka MT, Brosseron F, Ramirez A, Schmid M, Beschorner R, Halle A, Herms J, Neumann M, Barthélemy NR, Bateman RJ, Rizzu P, Heutink P, Dols-Icardo O, Höglinger G, Hermann A, Schneider A. Chatterjee M, et al. Among authors: mandelkow e. Nat Med. 2024 Jun;30(6):1771-1783. doi: 10.1038/s41591-024-02937-4. Epub 2024 Jun 18. Nat Med. 2024. PMID: 38890531 Free PMC article.
Spreading of Tau Protein Does Not Depend on Aggregation Propensity.
Rodrigues S, Anglada-Huguet M, Hochgräfe K, Kaniyappan S, Wegmann S, Mandelkow EM. Rodrigues S, et al. Among authors: mandelkow em. J Mol Neurosci. 2023 Oct;73(9-10):693-712. doi: 10.1007/s12031-023-02143-w. Epub 2023 Aug 22. J Mol Neurosci. 2023. PMID: 37606769 Free PMC article.
Initiation and modulation of Tau protein phase separation by the drug suramin.
Prince PR, Hochmair J, Brognaro H, Gevorgyan S, Franck M, Schubert R, Lorenzen K, Yazici S, Mandelkow E, Wegmann S, Betzel C. Prince PR, et al. Among authors: mandelkow e. Sci Rep. 2023 Mar 9;13(1):3963. doi: 10.1038/s41598-023-29846-9. Sci Rep. 2023. PMID: 36894559 Free PMC article.
370 results