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Page 1
Metabolic Flexibility in Leukemia-Adapt or Die.
Nachmias B, Schimmer AD. Nachmias B, et al. Among authors: schimmer ad. Cancer Cell. 2018 Nov 12;34(5):695-696. doi: 10.1016/j.ccell.2018.10.012. Cancer Cell. 2018. PMID: 30423291 Free article.
Outcome of patients who develop acute leukemia or myelodysplasia as a second malignancy after solid tumors treated surgically or with strategies that include chemotherapy and/or radiation.
Abdelhameed A, Pond GR, Mitsakakis N, Brandwein J, Chun K, Gupta V, Kamel-Reid S, Lipton JH, Minden MD, Schimmer A, Schuh A, Yee K, Messner HA. Abdelhameed A, et al. Cancer. 2008 Apr 1;112(7):1513-21. doi: 10.1002/cncr.23325. Cancer. 2008. PMID: 18286528 Free article.
Inhibition of mitochondrial translation as a therapeutic strategy for human acute myeloid leukemia.
Skrtić M, Sriskanthadevan S, Jhas B, Gebbia M, Wang X, Wang Z, Hurren R, Jitkova Y, Gronda M, Maclean N, Lai CK, Eberhard Y, Bartoszko J, Spagnuolo P, Rutledge AC, Datti A, Ketela T, Moffat J, Robinson BH, Cameron JH, Wrana J, Eaves CJ, Minden MD, Wang JC, Dick JE, Humphries K, Nislow C, Giaever G, Schimmer AD. Skrtić M, et al. Among authors: schimmer ad. Cancer Cell. 2011 Nov 15;20(5):674-88. doi: 10.1016/j.ccr.2011.10.015. Cancer Cell. 2011. PMID: 22094260 Free PMC article.
Inhibition of the Mitochondrial Protease ClpP as a Therapeutic Strategy for Human Acute Myeloid Leukemia.
Cole A, Wang Z, Coyaud E, Voisin V, Gronda M, Jitkova Y, Mattson R, Hurren R, Babovic S, Maclean N, Restall I, Wang X, Jeyaraju DV, Sukhai MA, Prabha S, Bashir S, Ramakrishnan A, Leung E, Qia YH, Zhang N, Combes KR, Ketela T, Lin F, Houry WA, Aman A, Al-Awar R, Zheng W, Wienholds E, Xu CJ, Dick J, Wang JC, Moffat J, Minden MD, Eaves CJ, Bader GD, Hao Z, Kornblau SM, Raught B, Schimmer AD. Cole A, et al. Among authors: schimmer ad. Cancer Cell. 2015 Jun 8;27(6):864-76. doi: 10.1016/j.ccell.2015.05.004. Cancer Cell. 2015. PMID: 26058080 Free PMC article.
A Phase 1 study of intravenous infusions of tigecycline in patients with acute myeloid leukemia.
Reed GA, Schiller GJ, Kambhampati S, Tallman MS, Douer D, Minden MD, Yee KW, Gupta V, Brandwein J, Jitkova Y, Gronda M, Hurren R, Shamas-Din A, Schuh AC, Schimmer AD. Reed GA, et al. Among authors: schimmer ad. Cancer Med. 2016 Nov;5(11):3031-3040. doi: 10.1002/cam4.845. Epub 2016 Oct 13. Cancer Med. 2016. PMID: 27734609 Free PMC article. Clinical Trial.
The thymidine dideoxynucleoside analog, alovudine, inhibits the mitochondrial DNA polymerase γ, impairs oxidative phosphorylation and promotes monocytic differentiation in acute myeloid leukemia.
Yehudai D, Liyanage SU, Hurren R, Rizoska B, Albertella M, Gronda M, Jeyaraju DV, Wang X, Barghout SH, MacLean N, Siriwardena TP, Jitkova Y, Targett-Adams P, Schimmer AD. Yehudai D, et al. Among authors: schimmer ad. Haematologica. 2019 May;104(5):963-972. doi: 10.3324/haematol.2018.195172. Epub 2018 Dec 20. Haematologica. 2019. PMID: 30573504 Free PMC article.
299 results