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WINDOW consortium: A path towards increased therapy efficacy against glioblastoma.
Abdul KU, Houweling M, Svensson F, Narayan RS, Cornelissen FMG, Küçükosmanoglu A, Metzakopian E, Watts C, Bailey D, Wurdinger T, Westerman BA. Abdul KU, et al. Among authors: metzakopian e. Drug Resist Updat. 2018 Sep;40:17-24. doi: 10.1016/j.drup.2018.10.001. Epub 2018 Oct 30. Drug Resist Updat. 2018. PMID: 30439622 Review.
Transcriptional repression of Plxnc1 by Lmx1a and Lmx1b directs topographic dopaminergic circuit formation.
Chabrat A, Brisson G, Doucet-Beaupré H, Salesse C, Schaan Profes M, Dovonou A, Akitegetse C, Charest J, Lemstra S, Côté D, Pasterkamp RJ, Abrudan MI, Metzakopian E, Ang SL, Lévesque M. Chabrat A, et al. Among authors: metzakopian e. Nat Commun. 2017 Oct 16;8(1):933. doi: 10.1038/s41467-017-01042-0. Nat Commun. 2017. PMID: 29038581 Free PMC article.
ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks.
Balmus G, Pilger D, Coates J, Demir M, Sczaniecka-Clift M, Barros AC, Woods M, Fu B, Yang F, Chen E, Ostermaier M, Stankovic T, Ponstingl H, Herzog M, Yusa K, Martinez FM, Durant ST, Galanty Y, Beli P, Adams DJ, Bradley A, Metzakopian E, Forment JV, Jackson SP. Balmus G, et al. Among authors: metzakopian e. Nat Commun. 2019 Jan 8;10(1):87. doi: 10.1038/s41467-018-07729-2. Nat Commun. 2019. PMID: 30622252 Free PMC article.
A conditional piggyBac transposition system for genetic screening in mice identifies oncogenic networks in pancreatic cancer.
Rad R, Rad L, Wang W, Strong A, Ponstingl H, Bronner IF, Mayho M, Steiger K, Weber J, Hieber M, Veltkamp C, Eser S, Geumann U, Öllinger R, Zukowska M, Barenboim M, Maresch R, Cadiñanos J, Friedrich M, Varela I, Constantino-Casas F, Sarver A, Ten Hoeve J, Prosser H, Seidler B, Bauer J, Heikenwälder M, Metzakopian E, Krug A, Ehmer U, Schneider G, Knösel T, Rümmele P, Aust D, Grützmann R, Pilarsky C, Ning Z, Wessels L, Schmid RM, Quail MA, Vassiliou G, Esposito I, Liu P, Saur D, Bradley A. Rad R, et al. Among authors: metzakopian e. Nat Genet. 2015 Jan;47(1):47-56. doi: 10.1038/ng.3164. Epub 2014 Dec 8. Nat Genet. 2015. PMID: 25485836
A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia.
Tzelepis K, Koike-Yusa H, De Braekeleer E, Li Y, Metzakopian E, Dovey OM, Mupo A, Grinkevich V, Li M, Mazan M, Gozdecka M, Ohnishi S, Cooper J, Patel M, McKerrell T, Chen B, Domingues AF, Gallipoli P, Teichmann S, Ponstingl H, McDermott U, Saez-Rodriguez J, Huntly BJP, Iorio F, Pina C, Vassiliou GS, Yusa K. Tzelepis K, et al. Among authors: metzakopian e. Cell Rep. 2016 Oct 18;17(4):1193-1205. doi: 10.1016/j.celrep.2016.09.079. Cell Rep. 2016. PMID: 27760321 Free PMC article.
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