Pomerantz RT - Search Results

1

Identification of a Small Interface between the Methyltransferase and RNA Polymerase of NS5 that is Essential for Zika Virus Replication.

Rusanov T, Kent T, Saeed M, Hoang TM, Thomas C, Rice CM, Pomerantz RT. Rusanov T, et al. Among authors: pomerantz rt. Sci Rep. 2018 Nov 26;8(1):17384. doi: 10.1038/s41598-018-35511-3. Sci Rep. 2018. PMID: 30478404 Free PMC article.

2

Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ.

Kent T, Chandramouly G, McDevitt SM, Ozdemir AY, Pomerantz RT. Kent T, et al. Among authors: pomerantz rt. Nat Struct Mol Biol. 2015 Mar;22(3):230-7. doi: 10.1038/nsmb.2961. Epub 2015 Feb 2. Nat Struct Mol Biol. 2015. PMID: 25643323 Free PMC article.

3

Small-Molecule Disruption of RAD52 Rings as a Mechanism for Precision Medicine in BRCA-Deficient Cancers.

Chandramouly G, McDevitt S, Sullivan K, Kent T, Luz A, Glickman JF, Andrake M, Skorski T, Pomerantz RT. Chandramouly G, et al. Among authors: pomerantz rt. Chem Biol. 2015 Nov 19;22(11):1491-1504. doi: 10.1016/j.chembiol.2015.10.003. Epub 2015 Nov 5. Chem Biol. 2015. PMID: 26548611 Free PMC article.

4

Polymerase θ is a robust terminal transferase that oscillates between three different mechanisms during end-joining.

Kent T, Mateos-Gomez PA, Sfeir A, Pomerantz RT. Kent T, et al. Among authors: pomerantz rt. Elife. 2016 Jun 17;5:e13740. doi: 10.7554/eLife.13740. Elife. 2016. PMID: 27311885 Free PMC article.

5

DNA polymerase θ specializes in incorporating synthetic expanded-size (xDNA) nucleotides.

Kent T, Rusanov TD, Hoang TM, Velema WA, Krueger AT, Copeland WC, Kool ET, Pomerantz RT. Kent T, et al. Among authors: pomerantz rt. Nucleic Acids Res. 2016 Nov 2;44(19):9381-9392. doi: 10.1093/nar/gkw721. Epub 2016 Sep 2. Nucleic Acids Res. 2016. PMID: 27591252 Free PMC article.

6

DNA Polymerase θ: A Unique Multifunctional End-Joining Machine.

Black SJ, Kashkina E, Kent T, Pomerantz RT. Black SJ, et al. Among authors: pomerantz rt. Genes (Basel). 2016 Sep 21;7(9):67. doi: 10.3390/genes7090067. Genes (Basel). 2016. PMID: 27657134 Free PMC article. Review.

7

Modification of 3' Terminal Ends of DNA and RNA Using DNA Polymerase θ Terminal Transferase Activity.

Hoang TM, Kent T, Pomerantz RT. Hoang TM, et al. Among authors: pomerantz rt. Bio Protoc. 2017 Jun 20;7(12):e2330. doi: 10.21769/BioProtoc.2330. Bio Protoc. 2017. PMID: 28824932 Free PMC article.

8

The helicase domain of Polθ counteracts RPA to promote alt-NHEJ.

Mateos-Gomez PA, Kent T, Deng SK, McDevitt S, Kashkina E, Hoang TM, Pomerantz RT, Sfeir A. Mateos-Gomez PA, et al. Among authors: pomerantz rt. Nat Struct Mol Biol. 2017 Dec;24(12):1116-1123. doi: 10.1038/nsmb.3494. Epub 2017 Oct 23. Nat Struct Mol Biol. 2017. PMID: 29058711 Free PMC article.

9

Polymerase θ-helicase efficiently unwinds DNA and RNA-DNA hybrids.

Ozdemir AY, Rusanov T, Kent T, Siddique LA, Pomerantz RT. Ozdemir AY, et al. Among authors: pomerantz rt. J Biol Chem. 2018 Apr 6;293(14):5259-5269. doi: 10.1074/jbc.RA117.000565. Epub 2018 Feb 14. J Biol Chem. 2018. PMID: 29444826 Free PMC article.

10

How RNA transcripts coordinate DNA recombination and repair.

McDevitt S, Rusanov T, Kent T, Chandramouly G, Pomerantz RT. McDevitt S, et al. Among authors: pomerantz rt. Nat Commun. 2018 Mar 15;9(1):1091. doi: 10.1038/s41467-018-03483-7. Nat Commun. 2018. PMID: 29545568 Free PMC article.

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