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The renin angiotensin system (RAS) mediates bifunctional growth regulation in melanoma and is a novel target for therapeutic intervention.
Renziehausen A, Wang H, Rao B, Weir L, Nigro CL, Lattanzio L, Merlano M, Vega-Rioja A, Del Carmen Fernandez-Carranco M, Hajji N, Matin R, Harwood C, Li S, Sim VR, O'Neill K, Evans A, Thompson A, Szlosarek P, Fleming C, Stebbing J, Proby C, Tzakos AG, Syed N, Crook T. Renziehausen A, et al. Among authors: thompson a. Oncogene. 2019 Mar;38(13):2320-2336. doi: 10.1038/s41388-018-0563-y. Epub 2018 Nov 26. Oncogene. 2019. PMID: 30478450 Free article.
Integrative mRNA profiling comparing cultured primary cells with clinical samples reveals PLK1 and C20orf20 as therapeutic targets in cutaneous squamous cell carcinoma.
Watt SA, Pourreyron C, Purdie K, Hogan C, Cole CL, Foster N, Pratt N, Bourdon JC, Appleyard V, Murray K, Thompson AM, Mao X, Mein C, Bruckner-Tuderman L, Evans A, McGrath JA, Proby CM, Foerster J, Leigh IM, South AP. Watt SA, et al. Among authors: thompson am. Oncogene. 2011 Nov 17;30(46):4666-77. doi: 10.1038/onc.2011.180. Epub 2011 May 23. Oncogene. 2011. PMID: 21602893 Free PMC article.
Breast cancer (non-metastatic).
Stebbing J, Delaney G, Thompson A. Stebbing J, et al. Among authors: thompson a. BMJ Clin Evid. 2011 Feb 8;2011:0102. BMJ Clin Evid. 2011. PMID: 21718560 Free PMC article. Review.
High frequency of complex TP53 mutations in CNS metastases from breast cancer.
Lo Nigro C, Vivenza D, Monteverde M, Lattanzio L, Gojis O, Garrone O, Comino A, Merlano M, Quinlan PR, Syed N, Purdie CA, Thompson A, Palmieri C, Crook T. Lo Nigro C, et al. Among authors: thompson a. Br J Cancer. 2012 Jan 17;106(2):397-404. doi: 10.1038/bjc.2011.464. Epub 2011 Dec 20. Br J Cancer. 2012. PMID: 22187033 Free PMC article.
NT5E (CD73) is epigenetically regulated in malignant melanoma and associated with metastatic site specificity.
Wang H, Lee S, Nigro CL, Lattanzio L, Merlano M, Monteverde M, Matin R, Purdie K, Mladkova N, Bergamaschi D, Harwood C, Syed N, Szlosarek P, Briasoulis E, McHugh A, Thompson A, Evans A, Leigh I, Fleming C, Inman GJ, Hatzimichael E, Proby C, Crook T. Wang H, et al. Among authors: thompson a. Br J Cancer. 2012 Apr 10;106(8):1446-52. doi: 10.1038/bjc.2012.95. Epub 2012 Mar 27. Br J Cancer. 2012. PMID: 22454080 Free PMC article.
8,062 results