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Integrated In Vivo Quantitative Proteomics and Nutrient Tracing Reveals Age-Related Metabolic Rewiring of Pancreatic β Cell Function.
Wortham M, Benthuysen JR, Wallace M, Savas JN, Mulas F, Divakaruni AS, Liu F, Albert V, Taylor BL, Sui Y, Saez E, Murphy AN, Yates JR 3rd, Metallo CM, Sander M. Wortham M, et al. Among authors: murphy an. Cell Rep. 2018 Dec 4;25(10):2904-2918.e8. doi: 10.1016/j.celrep.2018.11.031. Cell Rep. 2018. PMID: 30517875 Free PMC article.
Cell biology. A mitochondrial mystery, solved.
Divakaruni AS, Murphy AN. Divakaruni AS, et al. Among authors: murphy an. Science. 2012 Jul 6;337(6090):41-3. doi: 10.1126/science.1225601. Science. 2012. PMID: 22767917 No abstract available.
Thiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier.
Divakaruni AS, Wiley SE, Rogers GW, Andreyev AY, Petrosyan S, Loviscach M, Wall EA, Yadava N, Heuck AP, Ferrick DA, Henry RR, McDonald WG, Colca JR, Simon MI, Ciaraldi TP, Murphy AN. Divakaruni AS, et al. Among authors: murphy an. Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5422-7. doi: 10.1073/pnas.1303360110. Epub 2013 Mar 19. Proc Natl Acad Sci U S A. 2013. PMID: 23513224 Free PMC article.
IDH1 mutations alter citric acid cycle metabolism and increase dependence on oxidative mitochondrial metabolism.
Grassian AR, Parker SJ, Davidson SM, Divakaruni AS, Green CR, Zhang X, Slocum KL, Pu M, Lin F, Vickers C, Joud-Caldwell C, Chung F, Yin H, Handly ED, Straub C, Growney JD, Vander Heiden MG, Murphy AN, Pagliarini R, Metallo CM. Grassian AR, et al. Among authors: murphy an. Cancer Res. 2014 Jun 15;74(12):3317-31. doi: 10.1158/0008-5472.CAN-14-0772-T. Epub 2014 Apr 22. Cancer Res. 2014. PMID: 24755473 Free PMC article.
Regulation of substrate utilization by the mitochondrial pyruvate carrier.
Vacanti NM, Divakaruni AS, Green CR, Parker SJ, Henry RR, Ciaraldi TP, Murphy AN, Metallo CM. Vacanti NM, et al. Among authors: murphy an. Mol Cell. 2014 Nov 6;56(3):425-435. doi: 10.1016/j.molcel.2014.09.024. Epub 2014 Oct 30. Mol Cell. 2014. PMID: 25458843 Free PMC article.
Mitochondrial reprogramming induced by CaMKIIδ mediates hypertrophy decompensation.
Westenbrink BD, Ling H, Divakaruni AS, Gray CB, Zambon AC, Dalton ND, Peterson KL, Gu Y, Matkovich SJ, Murphy AN, Miyamoto S, Dorn GW 2nd, Heller Brown J. Westenbrink BD, et al. Among authors: murphy an. Circ Res. 2015 Feb 27;116(5):e28-39. doi: 10.1161/CIRCRESAHA.116.304682. Epub 2015 Jan 20. Circ Res. 2015. PMID: 25605649 Free PMC article.
137 results