Gu S - Search Results

1

RNA⁻Protein Interactions Prevent Long RNA Duplex Formation: Implications for the Design of RNA-Based Therapeutics.

Bindewald E, Dai L, Kasprzak WK, Kim T, Gu S, Shapiro BA. Bindewald E, et al. Among authors: gu s. Molecules. 2018 Dec 15;23(12):3329. doi: 10.3390/molecules23123329. Molecules. 2018. PMID: 30558267 Free PMC article.

2

Cytoplasmic Drosha activity generated by alternative splicing.

Dai L, Chen K, Youngren B, Kulina J, Yang A, Guo Z, Li J, Yu P, Gu S. Dai L, et al. Among authors: gu s. Nucleic Acids Res. 2016 Dec 1;44(21):10454-10466. doi: 10.1093/nar/gkw668. Epub 2016 Jul 28. Nucleic Acids Res. 2016. PMID: 27471035 Free PMC article.

3

Structural Differences between Pri-miRNA Paralogs Promote Alternative Drosha Cleavage and Expand Target Repertoires.

Bofill-De Ros X, Kasprzak WK, Bhandari Y, Fan L, Cavanaugh Q, Jiang M, Dai L, Yang A, Shao TJ, Shapiro BA, Wang YX, Gu S. Bofill-De Ros X, et al. Among authors: gu s. Cell Rep. 2019 Jan 8;26(2):447-459.e4. doi: 10.1016/j.celrep.2018.12.054. Cell Rep. 2019. PMID: 30625327 Free PMC article.

4

3' Uridylation Confers miRNAs with Non-canonical Target Repertoires.

Yang A, Bofill-De Ros X, Shao TJ, Jiang M, Li K, Villanueva P, Dai L, Gu S. Yang A, et al. Among authors: gu s. Mol Cell. 2019 Aug 8;75(3):511-522.e4. doi: 10.1016/j.molcel.2019.05.014. Epub 2019 Jun 6. Mol Cell. 2019. PMID: 31178353 Free PMC article.

5

AGO-bound mature miRNAs are oligouridylated by TUTs and subsequently degraded by DIS3L2.

Yang A, Shao TJ, Bofill-De Ros X, Lian C, Villanueva P, Dai L, Gu S. Yang A, et al. Among authors: gu s. Nat Commun. 2020 Jun 2;11(1):2765. doi: 10.1038/s41467-020-16533-w. Nat Commun. 2020. PMID: 32488030 Free PMC article.

6

Novel, abundant Drosha isoforms are deficient in miRNA processing in cancer cells.

Dai L, Hallmark L, Bofill De Ros X, Crouch H, Chen S, Shi T, Yang A, Lian C, Zhao Y, Tran B, Gu S. Dai L, et al. Among authors: gu s. RNA Biol. 2020 Nov;17(11):1603-1612. doi: 10.1080/15476286.2020.1813439. Epub 2020 Aug 30. RNA Biol. 2020. PMID: 32819190 Free PMC article.

7

Flexible pri-miRNA structures enable tunable production of 5' isomiRs.

Bofill-De Ros X, Hong Z, Birkenfeld B, Alamo-Ortiz S, Yang A, Dai L, Gu S. Bofill-De Ros X, et al. Among authors: gu s. RNA Biol. 2022;19(1):279-289. doi: 10.1080/15476286.2022.2025680. Epub 2021 Dec 31. RNA Biol. 2022. PMID: 35188062 Free PMC article.

8

Guidelines for the optimal design of miRNA-based shRNAs.

Bofill-De Ros X, Gu S. Bofill-De Ros X, et al. Among authors: gu s. Methods. 2016 Jul 1;103:157-66. doi: 10.1016/j.ymeth.2016.04.003. Epub 2016 Apr 12. Methods. 2016. PMID: 27083402 Free PMC article. Review.

9

IsomiRs: Expanding the miRNA repression toolbox beyond the seed.

Bofill-De Ros X, Yang A, Gu S. Bofill-De Ros X, et al. Among authors: gu s. Biochim Biophys Acta Gene Regul Mech. 2020 Apr;1863(4):194373. doi: 10.1016/j.bbagrm.2019.03.005. Epub 2019 Apr 4. Biochim Biophys Acta Gene Regul Mech. 2020. PMID: 30953728 Free PMC article. Review.

10

TENT2, TUT4, and TUT7 selectively regulate miRNA sequence and abundance.

Yang A, Bofill-De Ros X, Stanton R, Shao TJ, Villanueva P, Gu S. Yang A, et al. Among authors: gu s. Nat Commun. 2022 Sep 7;13(1):5260. doi: 10.1038/s41467-022-32969-8. Nat Commun. 2022. PMID: 36071058 Free PMC article.

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