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AKT/mTORC2 Inhibition Activates FOXO1 Function in CLL Cells Reducing B-Cell Receptor-Mediated Survival.
Cosimo E, Tarafdar A, Moles MW, Holroyd AK, Malik N, Catherwood MA, Hay J, Dunn KM, Macdonald AM, Guichard SM, O'Rourke D, Leach MT, Sansom OJ, Cosulich SC, McCaig AM, Michie AM. Cosimo E, et al. Among authors: hay j. Clin Cancer Res. 2019 Mar 1;25(5):1574-1587. doi: 10.1158/1078-0432.CCR-18-2036. Epub 2018 Dec 17. Clin Cancer Res. 2019. PMID: 30559170 Free PMC article.
Bioengineered niches that recreate physiological extracellular matrix organisation to support long-term haematopoietic stem cells.
Donnelly H, Ross E, Xiao Y, Hermantara R, Taqi AF, Doherty-Boyd WS, Cassels J, Tsimbouri PM, Dunn KM, Hay J, Cheng A, Meek RMD, Jain N, West C, Wheadon H, Michie AM, Peault B, West AG, Salmeron-Sanchez M, Dalby MJ. Donnelly H, et al. Among authors: hay j. Nat Commun. 2024 Jul 10;15(1):5791. doi: 10.1038/s41467-024-50054-0. Nat Commun. 2024. PMID: 38987295 Free PMC article.
IL-27 maintains cytotoxic Ly6C+ γδ T cells that arise from immature precursors.
Wiesheu R, Edwards SC, Hedley A, Hall H, Tosolini M, Fares da Silva MGF, Sumaria N, Castenmiller SM, Wardak L, Optaczy Y, Lynn A, Hill DG, Hayes AJ, Hay J, Kilbey A, Shaw R, Whyte D, Walsh PJ, Michie AM, Graham GJ, Manoharan A, Halsey C, Blyth K, Wolkers MC, Miller C, Pennington DJ, Jones GW, Fournie JJ, Bekiaris V, Coffelt SB. Wiesheu R, et al. Among authors: hay j. EMBO J. 2024 Jul;43(14):2878-2907. doi: 10.1038/s44318-024-00133-1. Epub 2024 May 30. EMBO J. 2024. PMID: 38816652 Free PMC article.
1,776 results