Patsoukis N - Search Results

1

A secreted PD-L1 splice variant that covalently dimerizes and mediates immunosuppression.

Mahoney KM, Shukla SA, Patsoukis N, Chaudhri A, Browne EP, Arazi A, Eisenhaure TM, Pendergraft WF 3rd, Hua P, Pham HC, Bu X, Zhu B, Hacohen N, Fritsch EF, Boussiotis VA, Wu CJ, Freeman GJ. Mahoney KM, et al. Among authors: patsoukis n. Cancer Immunol Immunother. 2019 Mar;68(3):421-432. doi: 10.1007/s00262-018-2282-1. Epub 2018 Dec 18. Cancer Immunol Immunother. 2019. PMID: 30564891 Free PMC article.

2

RIAM regulates the cytoskeletal distribution and activation of PLC-gamma1 in T cells.

Patsoukis N, Lafuente EM, Meraner P, Kim Js, Dombkowski D, Li L, Boussiotis VA. Patsoukis N, et al. Sci Signal. 2009 Dec 1;2(99):ra79. doi: 10.1126/scisignal.2000409. Sci Signal. 2009. PMID: 19952372 Free PMC article.

3

Selective effects of PD-1 on Akt and Ras pathways regulate molecular components of the cell cycle and inhibit T cell proliferation.

Patsoukis N, Brown J, Petkova V, Liu F, Li L, Boussiotis VA. Patsoukis N, et al. Sci Signal. 2012 Jun 26;5(230):ra46. doi: 10.1126/scisignal.2002796. Sci Signal. 2012. PMID: 22740686 Free PMC article.

4

Runx1 and Runx3 are involved in the generation and function of highly suppressive IL-17-producing T regulatory cells.

Li L, Patsoukis N, Petkova V, Boussiotis VA. Li L, et al. Among authors: patsoukis n. PLoS One. 2012;7(9):e45115. doi: 10.1371/journal.pone.0045115. Epub 2012 Sep 12. PLoS One. 2012. PMID: 22984619 Free PMC article.

5

PD-1 inhibits T cell proliferation by upregulating p27 and p15 and suppressing Cdc25A.

Patsoukis N, Sari D, Boussiotis VA. Patsoukis N, et al. Cell Cycle. 2012 Dec 1;11(23):4305-9. doi: 10.4161/cc.22135. Epub 2012 Oct 3. Cell Cycle. 2012. PMID: 23032366 Free PMC article.

6

Rap1-interacting adapter molecule (RIAM) associates with the plasma membrane via a proximity detector.

Wynne JP, Wu J, Su W, Mor A, Patsoukis N, Boussiotis VA, Hubbard SR, Philips MR. Wynne JP, et al. Among authors: patsoukis n. J Cell Biol. 2012 Oct 15;199(2):317-30. doi: 10.1083/jcb.201201157. Epub 2012 Oct 8. J Cell Biol. 2012. PMID: 23045549 Free PMC article.

7

PD-1 increases PTEN phosphatase activity while decreasing PTEN protein stability by inhibiting casein kinase 2.

Patsoukis N, Li L, Sari D, Petkova V, Boussiotis VA. Patsoukis N, et al. Mol Cell Biol. 2013 Aug;33(16):3091-8. doi: 10.1128/MCB.00319-13. Epub 2013 Jun 3. Mol Cell Biol. 2013. PMID: 23732914 Free PMC article.

8

Prostaglandin E2 promotes survival of naive UCB T cells via the Wnt/β-catenin pathway and alters immune reconstitution after UCBT.

Li L, Kim HT, Nellore A, Patsoukis N, Petkova V, McDonough S, Politikos I, Nikiforow S, Soiffer R, Antin JH, Ballen K, Cutler C, Ritz J, Boussiotis VA. Li L, et al. Among authors: patsoukis n. Blood Cancer J. 2014 Jan 17;4(1):e178. doi: 10.1038/bcj.2013.75. Blood Cancer J. 2014. PMID: 24442207 Free PMC article.

9

The cyclin dependent kinase inhibitor (R)-roscovitine mediates selective suppression of alloreactive human T cells but preserves pathogen-specific and leukemia-specific effectors.

Nellore A, Liu B, Patsoukis N, Boussiotis VA, Li L. Nellore A, et al. Among authors: patsoukis n. Clin Immunol. 2014 May-Jun;152(1-2):48-57. doi: 10.1016/j.clim.2014.02.015. Epub 2014 Mar 12. Clin Immunol. 2014. PMID: 24631965 Free PMC article.

10

PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation.

Patsoukis N, Bardhan K, Chatterjee P, Sari D, Liu B, Bell LN, Karoly ED, Freeman GJ, Petkova V, Seth P, Li L, Boussiotis VA. Patsoukis N, et al. Nat Commun. 2015 Mar 26;6:6692. doi: 10.1038/ncomms7692. Nat Commun. 2015. PMID: 25809635 Free PMC article.

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