Liu Z - Search Results

1

Novel selective TOPK inhibitor SKLB-C05 inhibits colorectal carcinoma growth and metastasis.

Gao T, Hu Q, Hu X, Lei Q, Feng Z, Yu X, Peng C, Song X, He H, Xu Y, Zuo W, Zeng J, Liu Z, Yu L. Gao T, et al. Among authors: liu z. Cancer Lett. 2019 Mar 31;445:11-23. doi: 10.1016/j.canlet.2018.12.016. Epub 2018 Dec 24. Cancer Lett. 2019. PMID: 30590102

2

Discovery of imidazo[2,1-b]thiazole HCV NS4B inhibitors exhibiting synergistic effect with other direct-acting antiviral agents.

Wang NY, Xu Y, Zuo WQ, Xiao KJ, Liu L, Zeng XX, You XY, Zhang LD, Gao C, Liu ZH, Ye TH, Xia Y, Xiong Y, Song XJ, Lei Q, Peng CT, Tang H, Yang SY, Wei YQ, Yu LT. Wang NY, et al. J Med Chem. 2015 Mar 26;58(6):2764-78. doi: 10.1021/jm501934n. Epub 2015 Mar 11. J Med Chem. 2015. PMID: 25710739

3

Identification of novel 2-aminothiazole conjugated nitrofuran as antitubercular and antibacterial agents.

Ran K, Gao C, Deng H, Lei Q, You X, Wang N, Shi Y, Liu Z, Wei W, Peng C, Xiong L, Xiao K, Yu L. Ran K, et al. Among authors: liu z. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3669-74. doi: 10.1016/j.bmcl.2016.05.088. Epub 2016 May 30. Bioorg Med Chem Lett. 2016. PMID: 27289321

4

Small Molecule TH-39 Potentially Targets Hec1/Nek2 Interaction and Exhibits Antitumor Efficacy in K562 Cells via G0/G1 Cell Cycle Arrest and Apoptosis Induction.

Zhu Y, Wei W, Ye T, Liu Z, Liu L, Luo Y, Zhang L, Gao C, Wang N, Yu L. Zhu Y, et al. Among authors: liu z, liu l. Cell Physiol Biochem. 2016;40(1-2):297-308. doi: 10.1159/000452546. Epub 2016 Nov 18. Cell Physiol Biochem. 2016. PMID: 27855372 Free article.

5

Synthesis and biological evaluation of N-(3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-7-yl)benzenesulfonamide derivatives as new BET bromodomain inhibitors for anti-hematologic malignancies activities.

Liu L, Zhu Y, Liu Z, Ye T, Zuo W, Peng C, Xiao K, Wang N, Yu L. Liu L, et al. Among authors: liu z. Mol Divers. 2017 Feb;21(1):125-136. doi: 10.1007/s11030-016-9707-6. Epub 2016 Nov 17. Mol Divers. 2017. PMID: 27858214

6

YLT-11, a novel PLK4 inhibitor, inhibits human breast cancer growth via inducing maladjusted centriole duplication and mitotic defect.

Lei Q, Xiong L, Xia Y, Feng Z, Gao T, Wei W, Song X, Ye T, Wang N, Peng C, Li Z, Liu Z, Yu L. Lei Q, et al. Among authors: liu z. Cell Death Dis. 2018 Oct 18;9(11):1066. doi: 10.1038/s41419-018-1071-2. Cell Death Dis. 2018. PMID: 30337519 Free PMC article.

7

Design, synthesis and biological evaluation of novel 1-phenyl phenanthridin-6(5H)-one derivatives as anti-tumor agents targeting TOPK.

Hu QF, Gao TT, Shi YJ, Lei Q, Liu ZH, Feng Q, Chen ZJ, Yu LT. Hu QF, et al. Eur J Med Chem. 2019 Jan 15;162:407-422. doi: 10.1016/j.ejmech.2018.11.007. Epub 2018 Nov 9. Eur J Med Chem. 2019. PMID: 30453248 Free article.

8

Synthesis and biological evaluation of benzomorpholine derivatives as novel EZH2 inhibitors for anti-non-small cell lung cancer activity.

Feng Q, He H, Gao T, Zhang Q, Liu Z, Tao X, Zhu Y, Zhang L, Yu L. Feng Q, et al. Among authors: liu z. Mol Divers. 2019 Aug;23(3):681-696. doi: 10.1007/s11030-018-9903-7. Epub 2019 Jan 5. Mol Divers. 2019. PMID: 30612258

9

Design, synthesis, and biological evaluation of 4,5-dihydro-[1,2,4]triazolo[4,3-f]pteridine derivatives as novel dual-PLK1/BRD4 inhibitors.

Wang NY, Xu Y, Xiao KJ, Zuo WQ, Zhu YX, Hu R, Wang WL, Shi YJ, Yu LT, Liu ZH. Wang NY, et al. Eur J Med Chem. 2020 Apr 1;191:112152. doi: 10.1016/j.ejmech.2020.112152. Epub 2020 Feb 17. Eur J Med Chem. 2020. PMID: 32088495

10

Design, synthesis and structure-activity relationship study of piperazinone-containing thieno[3,2-d]pyrimidine derivatives as new PI3Kδ inhibitors.

Wang NY, Zuo WQ, Hu R, Wang WL, Zhu YX, Xu Y, Yu LT, Liu ZH. Wang NY, et al. Bioorg Med Chem Lett. 2020 Oct 15;30(20):127479. doi: 10.1016/j.bmcl.2020.127479. Epub 2020 Aug 9. Bioorg Med Chem Lett. 2020. PMID: 32784091

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