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AWZ1066S, a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis.
Hong WD, Benayoud F, Nixon GL, Ford L, Johnston KL, Clare RH, Cassidy A, Cook DAN, Siu A, Shiotani M, Webborn PJH, Kavanagh S, Aljayyoussi G, Murphy E, Steven A, Archer J, Struever D, Frohberger SJ, Ehrens A, Hübner MP, Hoerauf A, Roberts AP, Hubbard ATM, Tate EW, Serwa RA, Leung SC, Qie L, Berry NG, Gusovsky F, Hemingway J, Turner JD, Taylor MJ, Ward SA, O'Neill PM. Hong WD, et al. Among authors: turner jd. Proc Natl Acad Sci U S A. 2019 Jan 22;116(4):1414-1419. doi: 10.1073/pnas.1816585116. Epub 2019 Jan 7. Proc Natl Acad Sci U S A. 2019. PMID: 30617067 Free PMC article.
Macrofilaricidal activity after doxycycline only treatment of Onchocerca volvulus in an area of Loa loa co-endemicity: a randomized controlled trial.
Turner JD, Tendongfor N, Esum M, Johnston KL, Langley RS, Ford L, Faragher B, Specht S, Mand S, Hoerauf A, Enyong P, Wanji S, Taylor MJ. Turner JD, et al. PLoS Negl Trop Dis. 2010 Apr 13;4(4):e660. doi: 10.1371/journal.pntd.0000660. PLoS Negl Trop Dis. 2010. PMID: 20405054 Free PMC article. Clinical Trial.
Minocycline as a re-purposed anti-Wolbachia macrofilaricide: superiority compared with doxycycline regimens in a murine infection model of human lymphatic filariasis.
Sharma R, Al Jayoussi G, Tyrer HE, Gamble J, Hayward L, Guimaraes AF, Davies J, Waterhouse D, Cook DA, Myhill LJ, Clare RH, Cassidy A, Steven A, Johnston KL, Ford L, Turner JD, Ward SA, Taylor MJ. Sharma R, et al. Among authors: turner jd. Sci Rep. 2016 Mar 21;6:23458. doi: 10.1038/srep23458. Sci Rep. 2016. PMID: 26996237 Free PMC article.
465 results