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Blood-brain barrier breakdown is an early biomarker of human cognitive dysfunction.
Nat Med. 2019 Feb;25(2):270-276. doi: 10.1038/s41591-018-0297-y. Epub 2019 Jan 14.
Nat Med. 2019.
PMID: 30643288
Free PMC article.
APOE4 leads to blood-brain barrier dysfunction predicting cognitive decline.
Montagne A, Nation DA, Sagare AP, Barisano G, Sweeney MD, Chakhoyan A, Pachicano M, Joe E, Nelson AR, D'Orazio LM, Buennagel DP, Harrington MG, Benzinger TLS, Fagan AM, Ringman JM, Schneider LS, Morris JC, Reiman EM, Caselli RJ, Chui HC, Tcw J, Chen Y, Pa J, Conti PS, Law M, Toga AW, Zlokovic BV.
Montagne A, et al. Among authors: buennagel dp.
Nature. 2020 May;581(7806):71-76. doi: 10.1038/s41586-020-2247-3. Epub 2020 Apr 29.
Nature. 2020.
PMID: 32376954
Free PMC article.
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Brain delivery of supplemental docosahexaenoic acid (DHA): A randomized placebo-controlled clinical trial.
Arellanes IC, Choe N, Solomon V, He X, Kavin B, Martinez AE, Kono N, Buennagel DP, Hazra N, Kim G, D'Orazio LM, McCleary C, Sagare A, Zlokovic BV, Hodis HN, Mack WJ, Chui HC, Harrington MG, Braskie MN, Schneider LS, Yassine HN.
Arellanes IC, et al. Among authors: buennagel dp.
EBioMedicine. 2020 Sep;59:102883. doi: 10.1016/j.ebiom.2020.102883. Epub 2020 Jul 17.
EBioMedicine. 2020.
PMID: 32690472
Free PMC article.
Clinical Trial.
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Resting heart rate (variability) and cognition relationships reveal cognitively healthy individuals with pathological amyloid/tau ratio.
Molloy C, Choy EH, Arechavala RJ, Buennagel D, Nolty A, Spezzaferri MR, Sin C, Rising S, Yu J, Al-Ezzi A, Kleinman MT, Kloner RA, Arakaki X.
Molloy C, et al.
Front Epidemiol. 2023;3:1168847. doi: 10.3389/fepid.2023.1168847. Epub 2023 May 26.
Front Epidemiol. 2023.
PMID: 37587981
Free PMC article.
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