Shankaran H - Search Results

1

A Systems Toxicology Approach for the Prediction of Kidney Toxicity and Its Mechanisms In Vitro.

Ramm S, Todorov P, Chandrasekaran V, Dohlman A, Monteiro MB, Pavkovic M, Muhlich J, Shankaran H, Chen WW, Mettetal JT, Vaidya VS. Ramm S, et al. Among authors: shankaran h. Toxicol Sci. 2019 May 1;169(1):54-69. doi: 10.1093/toxsci/kfz021. Toxicol Sci. 2019. PMID: 30649541 Free PMC article.

2

Multiscale Mathematical Model of Drug-Induced Proximal Tubule Injury: Linking Urinary Biomarkers to Epithelial Cell Injury and Renal Dysfunction.

Gebremichael Y, Lu J, Shankaran H, Helmlinger G, Mettetal J, Hallow KM. Gebremichael Y, et al. Among authors: shankaran h. Toxicol Sci. 2018 Mar 1;162(1):200-211. doi: 10.1093/toxsci/kfx239. Toxicol Sci. 2018. PMID: 29126144

3

Systems Pharmacology Model of Gastrointestinal Damage Predicts Species Differences and Optimizes Clinical Dosing Schedules.

Shankaran H, Cronin A, Barnes J, Sharma P, Tolsma J, Jasper P, Mettetal JT. Shankaran H, et al. CPT Pharmacometrics Syst Pharmacol. 2018 Jan;7(1):26-33. doi: 10.1002/psp4.12255. Epub 2017 Dec 6. CPT Pharmacometrics Syst Pharmacol. 2018. PMID: 28941225 Free PMC article.

4

Investigating nephrotoxicity of polymyxin derivatives by mapping renal distribution using mass spectrometry imaging.

Nilsson A, Goodwin RJ, Swales JG, Gallagher R, Shankaran H, Sathe A, Pradeepan S, Xue A, Keirstead N, Sasaki JC, Andren PE, Gupta A. Nilsson A, et al. Among authors: shankaran h. Chem Res Toxicol. 2015 Sep 21;28(9):1823-30. doi: 10.1021/acs.chemrestox.5b00262. Epub 2015 Sep 4. Chem Res Toxicol. 2015. PMID: 26293472

5

ERK oscillation-dependent gene expression patterns and deregulation by stress response.

Waters KM, Cummings BS, Shankaran H, Scholpa NE, Weber TJ. Waters KM, et al. Among authors: shankaran h. Chem Res Toxicol. 2014 Sep 15;27(9):1496-503. doi: 10.1021/tx500085u. Epub 2014 Aug 12. Chem Res Toxicol. 2014. PMID: 25068892 Free PMC article.

6

Inhibition of ERK oscillations by ionizing radiation and reactive oxygen species.

Shankaran H, Chrisler WB, Sontag RL, Weber TJ. Shankaran H, et al. Mol Carcinog. 2011 Jun;50(6):424-32. doi: 10.1002/mc.20724. Epub 2010 Dec 28. Mol Carcinog. 2011. PMID: 21557328

7

Basic fibroblast growth factor regulates persistent ERK oscillations in premalignant but not malignant JB6 cells.

Weber TJ, Shankaran H, Wiley HS, Opresko LK, Chrisler WB, Quesenberry RD. Weber TJ, et al. Among authors: shankaran h. J Invest Dermatol. 2010 May;130(5):1444-56. doi: 10.1038/jid.2009.383. Epub 2009 Dec 17. J Invest Dermatol. 2010. PMID: 20016498 Free article.

8

Using imaging methods to interrogate radiation-induced cell signaling.

Shankaran H, Weber TJ, von Neubeck C, Sowa MB. Shankaran H, et al. Radiat Res. 2012 Apr;177(4):496-507. doi: 10.1667/rr2669.1. Epub 2012 Mar 1. Radiat Res. 2012. PMID: 22380462 Review.

9

Time-dependent behavioral data from zebrafish reveals novel signatures of chemical toxicity using point of departure analysis.

Thomas DG, Shankaran H, Truong L, Tanguay RL, Waters KM. Thomas DG, et al. Among authors: shankaran h. Comput Toxicol. 2019 Feb;9:50-60. doi: 10.1016/j.comtox.2018.11.001. Epub 2018 Nov 10. Comput Toxicol. 2019. PMID: 31485548 Free PMC article.

10

Conserved host response to highly pathogenic avian influenza virus infection in human cell culture, mouse and macaque model systems.

McDermott JE, Shankaran H, Eisfeld AJ, Belisle SE, Neuman G, Li C, McWeeney S, Sabourin C, Kawaoka Y, Katze MG, Waters KM. McDermott JE, et al. Among authors: shankaran h. BMC Syst Biol. 2011 Nov 11;5:190. doi: 10.1186/1752-0509-5-190. BMC Syst Biol. 2011. PMID: 22074594 Free PMC article.

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