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Page 1
De novo designed proteins neutralize lethal snake venom toxins.
Vázquez Torres S, Benard Valle M, Mackessy SP, Menzies SK, Casewell NR, Ahmadi S, Burlet NJ, Muratspahić E, Sappington I, Overath MD, Rivera-de-Torre E, Ledergerber J, Laustsen AH, Boddum K, Bera AK, Kang A, Brackenbrough E, Cardoso IA, Crittenden EP, Edge RJ, Decarreau J, Ragotte RJ, Pillai AS, Abedi M, Han HL, Gerben SR, Murray A, Skotheim R, Stuart L, Stewart L, Fryer TJA, Jenkins TP, Baker D. Vázquez Torres S, et al. Among authors: fryer tja. Nature. 2025 Jan 15. doi: 10.1038/s41586-024-08393-x. Online ahead of print. Nature. 2025. PMID: 39814879
The striatum is an early, accurate indicator of amyloid burden using [11C]PiB in Down syndrome: comparison of two radiotracers.
McLachlan M, Bettcher B, McVea A, DiFillipo A, Zammit M, LeMerise L, Rouanet J, Price J, Tudorascu D, Laymon C, Keator D, Lao P, Brickman AM, Fryer T, Hartley S, Ances BM, Johnson S, Betthauser T, Stone CK, Zaman S, Handen B, Head E, Mapstone M, Christian BT. McLachlan M, et al. Among authors: fryer t. medRxiv [Preprint]. 2024 Dec 6:2024.12.04.24318526. doi: 10.1101/2024.12.04.24318526. medRxiv. 2024. PMID: 39677434 Free PMC article. Preprint.
V-ToCs (Venom Toxin Clustering): A tool for the investigation of sequence and structure similarities in snake venom toxins.
Kalogeropoulos K, Rosca V, O'Brien C, Christensen CR, Grahadi R, Sørensen CV, Overath MD, Espi DR, Jenkins DE, Keller UAD, Laustsen AH, Fryer TJ, Jenkins TP. Kalogeropoulos K, et al. Among authors: fryer tj. Toxicon. 2024 Nov 6;250:108088. doi: 10.1016/j.toxicon.2024.108088. Epub 2024 Aug 31. Toxicon. 2024. PMID: 39222754 Free article.
Blood inflammation relates to neuroinflammation and survival in frontotemporal lobar degeneration.
Malpetti M, Swann P, Tsvetanov KA, Chouliaras L, Strauss A, Chikaura T, Murley AG, Ashton NJ, Barker P, Jones PS, Fryer TD, Hong YT, Cope TE, Savulich G, Street D, Bevan-Jones WR, Rittman T, Blennow K, Zetterberg H, Aigbirhio FI, O'Brien JT, Rowe JB. Malpetti M, et al. Among authors: fryer td. Brain. 2024 Aug 19:awae269. doi: 10.1093/brain/awae269. Online ahead of print. Brain. 2024. PMID: 39155063 Free PMC article.
Outcomes and Mechanisms Associated With Selective Thalamic Neuronal Loss in Chronic Traumatic Brain Injury.
Woodrow RE, Grossac J, Hong YT, Winzeck S, Geeraerts T, Shah SA, Peattie ARD, Manktelow AE, Outtrim JG, Karakatsanis NA, Schiff ND, Fryer TD, Menon DK, Coles JP, Stamatakis EA. Woodrow RE, et al. Among authors: fryer td. JAMA Netw Open. 2024 Aug 1;7(8):e2426141. doi: 10.1001/jamanetworkopen.2024.26141. JAMA Netw Open. 2024. PMID: 39106064 Free PMC article.
De novo designed proteins neutralize lethal snake venom toxins.
Torres SV, Valle MB, Mackessy SP, Menzies SK, Casewell NR, Ahmadi S, Burlet NJ, Muratspahić E, Sappington I, Overath MD, Rivera-de-Torre E, Ledergerber J, Laustsen AH, Boddum K, Bera AK, Kang A, Brackenbrough E, Cardoso IA, Crittenden EP, Edge RJ, Decarreau J, Ragotte RJ, Pillai AS, Abedi M, Han HL, Gerben SR, Murray A, Skotheim R, Stuart L, Stewart L, Fryer TJA, Jenkins TP, Baker D. Torres SV, et al. Among authors: fryer tja. Res Sq [Preprint]. 2024 May 17:rs.3.rs-4402792. doi: 10.21203/rs.3.rs-4402792/v1. Res Sq. 2024. PMID: 38798548 Free PMC article. Preprint.
MINocyclinE to Reduce inflammation and blood-brain barrier leakage in small Vessel diseAse (MINERVA): A phase II, randomized, double-blind, placebo-controlled experimental medicine trial.
Brown RB, Tozer DJ, Loubière L, Harshfield EL, Hong YT, Fryer TD, Williams GB, Graves MJ, Aigbirhio FI, O'Brien JT, Markus HS. Brown RB, et al. Among authors: fryer td. Alzheimers Dement. 2024 Jun;20(6):3852-3863. doi: 10.1002/alz.13830. Epub 2024 Apr 17. Alzheimers Dement. 2024. PMID: 38629936 Free PMC article. Clinical Trial.
225 results