Ishikawa T - Search Results

1

Prediction of ALK mutations mediating ALK-TKIs resistance and drug re-purposing to overcome the resistance.

Okada K, Araki M, Sakashita T, Ma B, Kanada R, Yanagitani N, Horiike A, Koike S, Oh-Hara T, Watanabe K, Tamai K, Maemondo M, Nishio M, Ishikawa T, Okuno Y, Fujita N, Katayama R. Okada K, et al. Among authors: ishikawa t. EBioMedicine. 2019 Mar;41:105-119. doi: 10.1016/j.ebiom.2019.01.019. Epub 2019 Jan 17. EBioMedicine. 2019. PMID: 30662002 Free PMC article.

2

Structure-Based Drug Discovery for Prion Disease Using a Novel Binding Simulation.

Ishibashi D, Nakagaki T, Ishikawa T, Atarashi R, Watanabe K, Cruz FA, Hamada T, Nishida N. Ishibashi D, et al. Among authors: ishikawa t. EBioMedicine. 2016 Jul;9:238-249. doi: 10.1016/j.ebiom.2016.06.010. Epub 2016 Jun 8. EBioMedicine. 2016. PMID: 27333028 Free PMC article.

3

Identification of small molecule inhibitors for influenza a virus using in silico and in vitro approaches.

Makau JN, Watanabe K, Ishikawa T, Mizuta S, Hamada T, Kobayashi N, Nishida N. Makau JN, et al. Among authors: ishikawa t. PLoS One. 2017 Mar 8;12(3):e0173582. doi: 10.1371/journal.pone.0173582. eCollection 2017. PLoS One. 2017. PMID: 28273150 Free PMC article.

4

[Applications of the Fragment Molecular Orbital Method in Drug Discovery].

Ishikawa T. Ishikawa T. Yakugaku Zasshi. 2016;136(1):121-30. doi: 10.1248/yakushi.15-00230-5. Yakugaku Zasshi. 2016. PMID: 26725679 Free article. Japanese.

5

Novel Compounds Identified by Structure-Based Prion Disease Drug Discovery Using In Silico Screening Delay the Progression of an Illness in Prion-Infected Mice.

Ishibashi D, Ishikawa T, Mizuta S, Tange H, Nakagaki T, Hamada T, Nishida N. Ishibashi D, et al. Among authors: ishikawa t. Neurotherapeutics. 2020 Oct;17(4):1836-1849. doi: 10.1007/s13311-020-00903-9. Neurotherapeutics. 2020. PMID: 32767031 Free PMC article.

6

Protein-specific force field derived from the fragment molecular orbital method can improve protein-ligand binding interactions.

Chang L, Ishikawa T, Kuwata K, Takada S. Chang L, et al. Among authors: ishikawa t. J Comput Chem. 2013 May 30;34(14):1251-7. doi: 10.1002/jcc.23250. Epub 2013 Feb 19. J Comput Chem. 2013. PMID: 23420697

7

Prediction of peptide binding to a major histocompatibility complex class I molecule based on docking simulation.

Ishikawa T. Ishikawa T. J Comput Aided Mol Des. 2016 Oct;30(10):875-887. doi: 10.1007/s10822-016-9967-3. Epub 2016 Sep 13. J Comput Aided Mol Des. 2016. PMID: 27624584

8

Identification of Alprenolol Hydrochloride as an Anti-prion Compound Using Surface Plasmon Resonance Imaging.

Miyazaki Y, Ishikawa T, Kamatari YO, Nakagaki T, Takatsuki H, Ishibashi D, Kuwata K, Nishida N, Atarashi R. Miyazaki Y, et al. Among authors: ishikawa t. Mol Neurobiol. 2019 Jan;56(1):367-377. doi: 10.1007/s12035-018-1088-7. Epub 2018 Apr 27. Mol Neurobiol. 2019. PMID: 29704200

9

Novel and potent antimicrobial effects of caspofungin on drug-resistant Candida and bacteria.

Sumiyoshi M, Miyazaki T, Makau JN, Mizuta S, Tanaka Y, Ishikawa T, Makimura K, Hirayama T, Takazono T, Saijo T, Yamaguchi H, Shimamura S, Yamamoto K, Imamura Y, Sakamoto N, Obase Y, Izumikawa K, Yanagihara K, Kohno S, Mukae H. Sumiyoshi M, et al. Among authors: ishikawa t. Sci Rep. 2020 Oct 20;10(1):17745. doi: 10.1038/s41598-020-74749-8. Sci Rep. 2020. PMID: 33082485 Free PMC article.

10

Discovery and Structure-Based Optimization of Novel Atg4B Inhibitors for the Treatment of Castration-Resistant Prostate Cancer.

Kudo Y, Endo S, Fujita M, Ota A, Kamatari YO, Tanaka Y, Ishikawa T, Ikeda H, Okada T, Toyooka N, Fujimoto N, Matsunaga T, Ikari A. Kudo Y, et al. Among authors: ishikawa t. J Med Chem. 2022 Mar 24;65(6):4878-4892. doi: 10.1021/acs.jmedchem.1c02113. Epub 2022 Mar 4. J Med Chem. 2022. PMID: 35244402

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