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Page 1
Identifying genetic differences between bipolar disorder and major depression through multiple GWAS.
Panagiotaropoulou G, Hellberg KG, Coleman JRI, Seok D, Kalman J; Bipolar Disorder Working Group of the Psychiatric Genetics Consortium; Major Depressive Disorder Working Group of the Psychiatric Genetics Consortium; iPSYCH Study Consortium; Mitchell PB, Schofield PR, Forstner AJ, Bauer M, Scott LJ, Pato CN, Pato MT, Li QS, Kirov G, Landén M, Jonsson L, Müller-Myhsok B, Smoller JW, Binder EB, Brückl TM, Czamara D, der Auwera SV, Grabe HJ, Homuth G, Schmidt CO, Potash JB, DePaulo RJ, Goes FS, MacKinnon DF, Mondimore FM, Weissman MM, Shi J, Frye MA, Biernacka JM, Reif A, Witt SH, Kahn RR, Boks MM, Owen MJ, Gordon-Smith K, Mitchell BL, Martin NG, Medland SE, Jones L, Knowles JA, Levinson DF, O'Donovan MC, Lewis CM, Breen G, Werge T, Schork AJ, Ophoff R, Ripke S, Loohuis LO. Panagiotaropoulou G, et al. Among authors: bruckl tm. medRxiv [Preprint]. 2024 Jan 30:2024.01.29.24301816. doi: 10.1101/2024.01.29.24301816. medRxiv. 2024. PMID: 38410442 Free PMC article. Preprint.
Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment.
Binder EB, Salyakina D, Lichtner P, Wochnik GM, Ising M, Pütz B, Papiol S, Seaman S, Lucae S, Kohli MA, Nickel T, Künzel HE, Fuchs B, Majer M, Pfennig A, Kern N, Brunner J, Modell S, Baghai T, Deiml T, Zill P, Bondy B, Rupprecht R, Messer T, Köhnlein O, Dabitz H, Brückl T, Müller N, Pfister H, Lieb R, Mueller JC, Lõhmussaar E, Strom TM, Bettecken T, Meitinger T, Uhr M, Rein T, Holsboer F, Muller-Myhsok B. Binder EB, et al. Among authors: bruckl t. Nat Genet. 2004 Dec;36(12):1319-25. doi: 10.1038/ng1479. Epub 2004 Nov 21. Nat Genet. 2004. PMID: 15565110
Somatization in major depression--clinical features and genetic associations.
Klengel T, Heck A, Pfister H, Brückl T, Hennings JM, Menke A, Czamara D, Müller-Myhsok B, Ising M. Klengel T, et al. Among authors: bruckl t. Acta Psychiatr Scand. 2011 Oct;124(4):317-28. doi: 10.1111/j.1600-0447.2011.01743.x. Epub 2011 Aug 13. Acta Psychiatr Scand. 2011. PMID: 21838737
Resistance to antidepressant treatment is associated with polymorphisms in the leptin gene, decreased leptin mRNA expression, and decreased leptin serum levels.
Kloiber S, Ripke S, Kohli MA, Reppermund S, Salyakina D, Uher R, McGuffin P, Perlis RH, Hamilton SP, Pütz B, Hennings J, Brückl T, Klengel T, Bettecken T, Ising M, Uhr M, Dose T, Unschuld PG, Zihl J, Binder E, Müller-Myhsok B, Holsboer F, Lucae S. Kloiber S, et al. Among authors: bruckl t. Eur Neuropsychopharmacol. 2013 Jul;23(7):653-62. doi: 10.1016/j.euroneuro.2012.08.010. Epub 2012 Sep 29. Eur Neuropsychopharmacol. 2013. PMID: 23026132 Free PMC article.
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