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The glutathione cycle shapes synaptic glutamate activity.
Sedlak TW, Paul BD, Parker GM, Hester LD, Snowman AM, Taniguchi Y, Kamiya A, Snyder SH, Sawa A. Sedlak TW, et al. Among authors: hester ld. Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2701-2706. doi: 10.1073/pnas.1817885116. Epub 2019 Jan 28. Proc Natl Acad Sci U S A. 2019. PMID: 30692251 Free PMC article.
Glutathione is a physiologic reservoir of neuronal glutamate.
Koga M, Serritella AV, Messmer MM, Hayashi-Takagi A, Hester LD, Snyder SH, Sawa A, Sedlak TW. Koga M, et al. Among authors: hester ld. Biochem Biophys Res Commun. 2011 Jun 17;409(4):596-602. doi: 10.1016/j.bbrc.2011.04.087. Epub 2011 Apr 24. Biochem Biophys Res Commun. 2011. PMID: 21539809 Free PMC article.
Akt as a mediator of cell death.
Luo HR, Hattori H, Hossain MA, Hester L, Huang Y, Lee-Kwon W, Donowitz M, Nagata E, Snyder SH. Luo HR, et al. Proc Natl Acad Sci U S A. 2003 Sep 30;100(20):11712-7. doi: 10.1073/pnas.1634990100. Epub 2003 Sep 22. Proc Natl Acad Sci U S A. 2003. PMID: 14504398 Free PMC article.
Bilirubin Links Heme Metabolism to Neuroprotection by Scavenging Superoxide.
Vasavda C, Kothari R, Malla AP, Tokhunts R, Lin A, Ji M, Ricco C, Xu R, Saavedra HG, Sbodio JI, Snowman AM, Albacarys L, Hester L, Sedlak TW, Paul BD, Snyder SH. Vasavda C, et al. Cell Chem Biol. 2019 Oct 17;26(10):1450-1460.e7. doi: 10.1016/j.chembiol.2019.07.006. Epub 2019 Jul 25. Cell Chem Biol. 2019. PMID: 31353321 Free PMC article.
Neuroprotection by pharmacologic blockade of the GAPDH death cascade.
Hara MR, Thomas B, Cascio MB, Bae BI, Hester LD, Dawson VL, Dawson TM, Sawa A, Snyder SH. Hara MR, et al. Among authors: hester ld. Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3887-9. doi: 10.1073/pnas.0511321103. Epub 2006 Feb 27. Proc Natl Acad Sci U S A. 2006. PMID: 16505364 Free PMC article.
34 results