Overall CM - Search Results

1

An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient.

Quancard J, Klein T, Fung SY, Renatus M, Hughes N, Israël L, Priatel JJ, Kang S, Blank MA, Viner RI, Blank J, Schlapbach A, Erbel P, Kizhakkedathu J, Villard F, Hersperger R, Turvey SE, Eder J, Bornancin F, Overall CM. Quancard J, et al. Among authors: overall cm. Nat Chem Biol. 2019 Mar;15(3):304-313. doi: 10.1038/s41589-018-0222-1. Epub 2019 Jan 28. Nat Chem Biol. 2019. PMID: 30692685

2

Isotopic labeling of terminal amines in complex samples identifies protein N-termini and protease cleavage products.

Kleifeld O, Doucet A, auf dem Keller U, Prudova A, Schilling O, Kainthan RK, Starr AE, Foster LJ, Kizhakkedathu JN, Overall CM. Kleifeld O, et al. Among authors: overall cm. Nat Biotechnol. 2010 Mar;28(3):281-8. doi: 10.1038/nbt.1611. Epub 2010 Mar 7. Nat Biotechnol. 2010. PMID: 20208520

3

Proteome-wide analysis of protein carboxy termini: C terminomics.

Schilling O, Barré O, Huesgen PF, Overall CM. Schilling O, et al. Among authors: overall cm. Nat Methods. 2010 Jul;7(7):508-11. doi: 10.1038/nmeth.1467. Epub 2010 Jun 6. Nat Methods. 2010. PMID: 20526347

4

Identification of proteolytic products and natural protein N-termini by Terminal Amine Isotopic Labeling of Substrates (TAILS).

Doucet A, Kleifeld O, Kizhakkedathu JN, Overall CM. Doucet A, et al. Among authors: overall cm. Methods Mol Biol. 2011;753:273-87. doi: 10.1007/978-1-61779-148-2_18. Methods Mol Biol. 2011. PMID: 21604129

5

Development of soluble ester-linked aldehyde polymers for proteomics.

Beaudette P, Rossi NA, Huesgen PF, Yu X, Shenoi RA, Doucet A, Overall CM, Kizhakkedathu JN. Beaudette P, et al. Among authors: overall cm. Anal Chem. 2011 Sep 1;83(17):6500-10. doi: 10.1021/ac200419p. Epub 2011 Aug 11. Anal Chem. 2011. PMID: 21774540

6

Identifying and quantifying proteolytic events and the natural N terminome by terminal amine isotopic labeling of substrates.

Kleifeld O, Doucet A, Prudova A, auf dem Keller U, Gioia M, Kizhakkedathu JN, Overall CM. Kleifeld O, et al. Among authors: overall cm. Nat Protoc. 2011 Sep 22;6(10):1578-611. doi: 10.1038/nprot.2011.382. Nat Protoc. 2011. PMID: 21959240

7

The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling.

Klein T, Fung SY, Renner F, Blank MA, Dufour A, Kang S, Bolger-Munro M, Scurll JM, Priatel JJ, Schweigler P, Melkko S, Gold MR, Viner RI, Régnier CH, Turvey SE, Overall CM. Klein T, et al. Among authors: overall cm. Nat Commun. 2015 Nov 3;6:8777. doi: 10.1038/ncomms9777. Nat Commun. 2015. PMID: 26525107 Free PMC article.

8

Quantitative proteomics and terminomics to elucidate the role of ubiquitination and proteolysis in adaptive immunity.

Klein T, Viner RI, Overall CM. Klein T, et al. Among authors: overall cm. Philos Trans A Math Phys Eng Sci. 2016 Oct 28;374(2079):20150372. doi: 10.1098/rsta.2015.0372. Philos Trans A Math Phys Eng Sci. 2016. PMID: 27644975 Free PMC article. Review.

9

Proteolytic Cleavage-Mechanisms, Function, and "Omic" Approaches for a Near-Ubiquitous Posttranslational Modification.

Klein T, Eckhard U, Dufour A, Solis N, Overall CM. Klein T, et al. Among authors: overall cm. Chem Rev. 2018 Feb 14;118(3):1137-1168. doi: 10.1021/acs.chemrev.7b00120. Epub 2017 Dec 21. Chem Rev. 2018. PMID: 29265812 Review.

10

N-Terminomics TAILS Identifies Host Cell Substrates of Poliovirus and Coxsackievirus B3 3C Proteinases That Modulate Virus Infection.

Jagdeo JM, Dufour A, Klein T, Solis N, Kleifeld O, Kizhakkedathu J, Luo H, Overall CM, Jan E. Jagdeo JM, et al. Among authors: overall cm. J Virol. 2018 Mar 28;92(8):e02211-17. doi: 10.1128/JVI.02211-17. Print 2018 Apr 15. J Virol. 2018. PMID: 29437971 Free PMC article.

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