Grond S - Search Results

1

Cyanobacterial antimetabolite 7-deoxy-sedoheptulose blocks the shikimate pathway to inhibit the growth of prototrophic organisms.

Brilisauer K, Rapp J, Rath P, Schöllhorn A, Bleul L, Weiß E, Stahl M, Grond S, Forchhammer K. Brilisauer K, et al. Among authors: grond s. Nat Commun. 2019 Feb 1;10(1):545. doi: 10.1038/s41467-019-08476-8. Nat Commun. 2019. PMID: 30710081 Free PMC article.

2

Lugdunin amplifies innate immune responses in the skin in synergy with host- and microbiota-derived factors.

Bitschar K, Sauer B, Focken J, Dehmer H, Moos S, Konnerth M, Schilling NA, Grond S, Kalbacher H, Kurschus FC, Götz F, Krismer B, Peschel A, Schittek B. Bitschar K, et al. Among authors: grond s. Nat Commun. 2019 Jun 21;10(1):2730. doi: 10.1038/s41467-019-10646-7. Nat Commun. 2019. PMID: 31227691 Free PMC article.

3

A bioactive molecule made by unusual salvage of radical SAM enzyme byproduct 5-deoxyadenosine blurs the boundary of primary and secondary metabolism.

Rapp J, Rath P, Kilian J, Brilisauer K, Grond S, Forchhammer K. Rapp J, et al. Among authors: grond s. J Biol Chem. 2021 Jan-Jun;296:100621. doi: 10.1016/j.jbc.2021.100621. Epub 2021 Mar 31. J Biol Chem. 2021. PMID: 33811856 Free PMC article.

4

Hybrid Chemoenzymatic Synthesis of C₇ -Sugars for Molecular Evidence of in vivo Shikimate Pathway Inhibition.

Rath P, Rapp J, Brilisauer K, Braun M, Kolukisaoglu Ü, Forchhammer K, Grond S. Rath P, et al. Among authors: grond s. Chembiochem. 2022 Jul 5;23(13):e202200241. doi: 10.1002/cbic.202200241. Epub 2022 May 23. Chembiochem. 2022. PMID: 35508894 Free PMC article.

5

Human commensals producing a novel antibiotic impair pathogen colonization.

Zipperer A, Konnerth MC, Laux C, Berscheid A, Janek D, Weidenmaier C, Burian M, Schilling NA, Slavetinsky C, Marschal M, Willmann M, Kalbacher H, Schittek B, Brötz-Oesterhelt H, Grond S, Peschel A, Krismer B. Zipperer A, et al. Among authors: grond s. Nature. 2016 Jul 28;535(7613):511-6. doi: 10.1038/nature18634. Nature. 2016. PMID: 27466123

6

Resurrecting ancestral antibiotics: unveiling the origins of modern lipid II targeting glycopeptides.

Hansen MH, Adamek M, Iftime D, Petras D, Schuseil F, Grond S, Stegmann E, Cryle MJ, Ziemert N. Hansen MH, et al. Among authors: grond s. Nat Commun. 2023 Nov 29;14(1):7842. doi: 10.1038/s41467-023-43451-4. Nat Commun. 2023. PMID: 38030603 Free PMC article.

7

The antimicrobial fibupeptide lugdunin forms water-filled channel structures in lipid membranes.

Ruppelt D, Trollmann MFW, Dema T, Wirtz SN, Flegel H, Mönnikes S, Grond S, Böckmann RA, Steinem C. Ruppelt D, et al. Among authors: grond s. Nat Commun. 2024 Apr 25;15(1):3521. doi: 10.1038/s41467-024-47803-6. Nat Commun. 2024. PMID: 38664456 Free PMC article.

8

A two-step sulfation in antibiotic biosynthesis requires a type III polyketide synthase.

Tang X, Eitel K, Kaysser L, Kulik A, Grond S, Gust B. Tang X, et al. Among authors: grond s. Nat Chem Biol. 2013 Oct;9(10):610-5. doi: 10.1038/nchembio.1310. Epub 2013 Aug 4. Nat Chem Biol. 2013. PMID: 23912167

9

Unusual N-prenylation in diazepinomicin biosynthesis: the farnesylation of a benzodiazepine substrate is catalyzed by a new member of the ABBA prenyltransferase superfamily.

Bonitz T, Zubeil F, Grond S, Heide L. Bonitz T, et al. Among authors: grond s. PLoS One. 2013 Dec 23;8(12):e85707. doi: 10.1371/journal.pone.0085707. eCollection 2013. PLoS One. 2013. PMID: 24376894 Free PMC article.

10

Caprazamycins: Biosynthesis and structure activity relationship studies.

Wiker F, Hauck N, Grond S, Gust B. Wiker F, et al. Among authors: grond s. Int J Med Microbiol. 2019 Jul;309(5):319-324. doi: 10.1016/j.ijmm.2019.05.004. Epub 2019 May 24. Int J Med Microbiol. 2019. PMID: 31138496 Review.

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