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Inhibiting Glutamine-Dependent mTORC1 Activation Ameliorates Liver Cancers Driven by β-Catenin Mutations.
Adebayo Michael AO, Ko S, Tao J, Moghe A, Yang H, Xu M, Russell JO, Pradhan-Sundd T, Liu S, Singh S, Poddar M, Monga JS, Liu P, Oertel M, Ranganathan S, Singhi A, Rebouissou S, Zucman-Rossi J, Ribback S, Calvisi D, Qvartskhava N, Görg B, Häussinger D, Chen X, Monga SP. Adebayo Michael AO, et al. Among authors: ranganathan s. Cell Metab. 2019 May 7;29(5):1135-1150.e6. doi: 10.1016/j.cmet.2019.01.002. Epub 2019 Jan 31. Cell Metab. 2019. PMID: 30713111 Free PMC article.
Activation of β-catenin and Yap1 in human hepatoblastoma and induction of hepatocarcinogenesis in mice.
Tao J, Calvisi DF, Ranganathan S, Cigliano A, Zhou L, Singh S, Jiang L, Fan B, Terracciano L, Armeanu-Ebinger S, Ribback S, Dombrowski F, Evert M, Chen X, Monga SPS. Tao J, et al. Among authors: ranganathan s. Gastroenterology. 2014 Sep;147(3):690-701. doi: 10.1053/j.gastro.2014.05.004. Epub 2014 May 14. Gastroenterology. 2014. PMID: 24837480 Free PMC article.
Coordinated Activities of Multiple Myc-dependent and Myc-independent Biosynthetic Pathways in Hepatoblastoma.
Wang H, Lu J, Edmunds LR, Kulkarni S, Dolezal J, Tao J, Ranganathan S, Jackson L, Fromherz M, Beer-Stolz D, Uppala R, Bharathi S, Monga SP, Goetzman ES, Prochownik EV. Wang H, et al. Among authors: ranganathan s. J Biol Chem. 2016 Dec 16;291(51):26241-26251. doi: 10.1074/jbc.M116.754218. Epub 2016 Oct 13. J Biol Chem. 2016. PMID: 27738108 Free PMC article.
Dual catenin loss in murine liver causes tight junctional deregulation and progressive intrahepatic cholestasis.
Pradhan-Sundd T, Zhou L, Vats R, Jiang A, Molina L, Singh S, Poddar M, Russell J, Stolz DB, Oertel M, Apte U, Watkins S, Ranganathan S, Nejak-Bowen KN, Sundd P, Monga SP. Pradhan-Sundd T, et al. Among authors: ranganathan s. Hepatology. 2018 Jun;67(6):2320-2337. doi: 10.1002/hep.29585. Epub 2018 Apr 19. Hepatology. 2018. PMID: 29023813 Free PMC article.
1,048 results