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Boron-Pleuromutilins as Anti- Wolbachia Agents with Potential for Treatment of Onchocerciasis and Lymphatic Filariasis.
Jacobs RT, Lunde CS, Freund YR, Hernandez V, Li X, Xia Y, Carter DS, Berry PW, Halladay J, Rock F, Stefanakis R, Easom E, Plattner JJ, Ford L, Johnston KL, Cook DAN, Clare R, Cassidy A, Myhill L, Tyrer H, Gamble J, Guimaraes AF, Steven A, Lenz F, Ehrens A, Frohberger SJ, Koschel M, Hoerauf A, Hübner MP, McNamara CW, Bakowski MA, Turner JD, Taylor MJ, Ward SA. Jacobs RT, et al. Among authors: johnston kl. J Med Chem. 2019 Mar 14;62(5):2521-2540. doi: 10.1021/acs.jmedchem.8b01854. Epub 2019 Feb 26. J Med Chem. 2019. PMID: 30730745 Free PMC article.
Functional conservation of the lipid II biosynthesis pathway in the cell wall-less bacteria Chlamydia and Wolbachia: why is lipid II needed?
Henrichfreise B, Schiefer A, Schneider T, Nzukou E, Poellinger C, Hoffmann TJ, Johnston KL, Moelleken K, Wiedemann I, Pfarr K, Hoerauf A, Sahl HG. Henrichfreise B, et al. Among authors: johnston kl. Mol Microbiol. 2009 Sep;73(5):913-23. doi: 10.1111/j.1365-2958.2009.06815.x. Epub 2009 Jul 28. Mol Microbiol. 2009. PMID: 19656295 Free article.
Macrofilaricidal activity after doxycycline only treatment of Onchocerca volvulus in an area of Loa loa co-endemicity: a randomized controlled trial.
Turner JD, Tendongfor N, Esum M, Johnston KL, Langley RS, Ford L, Faragher B, Specht S, Mand S, Hoerauf A, Enyong P, Wanji S, Taylor MJ. Turner JD, et al. Among authors: johnston kl. PLoS Negl Trop Dis. 2010 Apr 13;4(4):e660. doi: 10.1371/journal.pntd.0000660. PLoS Negl Trop Dis. 2010. PMID: 20405054 Free PMC article. Clinical Trial.
Wolbachia filarial interactions.
Taylor MJ, Voronin D, Johnston KL, Ford L. Taylor MJ, et al. Among authors: johnston kl. Cell Microbiol. 2013 Apr;15(4):520-6. doi: 10.1111/cmi.12084. Epub 2012 Dec 24. Cell Microbiol. 2013. PMID: 23210448 Review.
89 results