Sharpe AH - Search Results

1

Costimulation of type-2 innate lymphoid cells by GITR promotes effector function and ameliorates type 2 diabetes.

Galle-Treger L, Sankaranarayanan I, Hurrell BP, Howard E, Lo R, Maazi H, Lewis G, Banie H, Epstein AL, Hu P, Rehan VK, Gilliland FD, Allayee H, Soroosh P, Sharpe AH, Akbari O. Galle-Treger L, et al. Among authors: sharpe ah. Nat Commun. 2019 Feb 12;10(1):713. doi: 10.1038/s41467-019-08449-x. Nat Commun. 2019. PMID: 30755607 Free PMC article.

2

Antigen-specific regulatory T cells develop via the ICOS-ICOS-ligand pathway and inhibit allergen-induced airway hyperreactivity.

Akbari O, Freeman GJ, Meyer EH, Greenfield EA, Chang TT, Sharpe AH, Berry G, DeKruyff RH, Umetsu DT. Akbari O, et al. Among authors: sharpe ah. Nat Med. 2002 Sep;8(9):1024-32. doi: 10.1038/nm745. Epub 2002 Jul 29. Nat Med. 2002. PMID: 12145647

3

ICOS/ICOSL interaction is required for CD4+ invariant NKT cell function and homeostatic survival.

Akbari O, Stock P, Meyer EH, Freeman GJ, Sharpe AH, Umetsu DT, DeKruyff RH. Akbari O, et al. Among authors: sharpe ah. J Immunol. 2008 Apr 15;180(8):5448-56. doi: 10.4049/jimmunol.180.8.5448. J Immunol. 2008. PMID: 18390727 Free PMC article.

4

PD-L1 and PD-L2 modulate airway inflammation and iNKT-cell-dependent airway hyperreactivity in opposing directions.

Akbari O, Stock P, Singh AK, Lombardi V, Lee WL, Freeman GJ, Sharpe AH, Umetsu DT, Dekruyff RH. Akbari O, et al. Among authors: sharpe ah. Mucosal Immunol. 2010 Jan;3(1):81-91. doi: 10.1038/mi.2009.112. Epub 2009 Sep 9. Mucosal Immunol. 2010. PMID: 19741598 Free PMC article.

5

Lack of PD-L1 expression by iNKT cells improves the course of influenza A infection.

Maazi H, Singh AK, Speak AO, Lombardi V, Lam J, Khoo B, Inn KS, Sharpe AH, Jung JU, Akbari O. Maazi H, et al. Among authors: sharpe ah. PLoS One. 2013;8(3):e59599. doi: 10.1371/journal.pone.0059599. Epub 2013 Mar 15. PLoS One. 2013. PMID: 23555047 Free PMC article.

6

Inclusion of CD80 in HSV targets the recombinant virus to PD-L1 on DCs and allows productive infection and robust immune responses.

Mott KR, Allen SJ, Zandian M, Akbari O, Hamrah P, Maazi H, Wechsler SL, Sharpe AH, Freeman GJ, Ghiasi H. Mott KR, et al. Among authors: sharpe ah. PLoS One. 2014 Jan 27;9(1):e87617. doi: 10.1371/journal.pone.0087617. eCollection 2014. PLoS One. 2014. PMID: 24475315 Free PMC article.

7

ICOS:ICOS-ligand interaction is required for type 2 innate lymphoid cell function, homeostasis, and induction of airway hyperreactivity.

Maazi H, Patel N, Sankaranarayanan I, Suzuki Y, Rigas D, Soroosh P, Freeman GJ, Sharpe AH, Akbari O. Maazi H, et al. Among authors: sharpe ah. Immunity. 2015 Mar 17;42(3):538-51. doi: 10.1016/j.immuni.2015.02.007. Epub 2015 Mar 10. Immunity. 2015. PMID: 25769613 Free PMC article.

8

Type 2 innate lymphoid cell suppression by regulatory T cells attenuates airway hyperreactivity and requires inducible T-cell costimulator-inducible T-cell costimulator ligand interaction.

Rigas D, Lewis G, Aron JL, Wang B, Banie H, Sankaranarayanan I, Galle-Treger L, Maazi H, Lo R, Freeman GJ, Sharpe AH, Soroosh P, Akbari O. Rigas D, et al. Among authors: sharpe ah. J Allergy Clin Immunol. 2017 May;139(5):1468-1477.e2. doi: 10.1016/j.jaci.2016.08.034. Epub 2016 Oct 4. J Allergy Clin Immunol. 2017. PMID: 27717665 Free PMC article.

9

A CRISPR-Cas9 delivery system for in vivo screening of genes in the immune system.

LaFleur MW, Nguyen TH, Coxe MA, Yates KB, Trombley JD, Weiss SA, Brown FD, Gillis JE, Coxe DJ, Doench JG, Haining WN, Sharpe AH. LaFleur MW, et al. Among authors: sharpe ah. Nat Commun. 2019 Apr 10;10(1):1668. doi: 10.1038/s41467-019-09656-2. Nat Commun. 2019. PMID: 30971695 Free PMC article.

10

PD-1 pathway regulates ILC2 metabolism and PD-1 agonist treatment ameliorates airway hyperreactivity.

Helou DG, Shafiei-Jahani P, Lo R, Howard E, Hurrell BP, Galle-Treger L, Painter JD, Lewis G, Soroosh P, Sharpe AH, Akbari O. Helou DG, et al. Among authors: sharpe ah. Nat Commun. 2020 Aug 10;11(1):3998. doi: 10.1038/s41467-020-17813-1. Nat Commun. 2020. PMID: 32778730 Free PMC article.

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