ORP4L couples IP3 to ITPR1 in control of endoplasmic reticulum calcium release.
Cao X, Chen J, Li D, Xie P, Xu M, Lin W, Li S, Pan G, Tang Y, Xu J, Olkkonen VM, Yan D, Zhong W.
Cao X, et al. Among authors: xu m, xu j.
FASEB J. 2019 Dec;33(12):13852-13865. doi: 10.1096/fj.201900933RR. Epub 2019 Oct 23.
FASEB J. 2019.
PMID: 31648575
These data support a novel model in which ORP4L is a cofactor of ITPR1, which increases ITPR1 sensitivity to IP(3) and enables ER Ca(2+) release.-Cao, X., Chen, J., Li, D., Xie, P., Xu, M., Lin, W., Li, S., Pan, G., Tang, Y., Xu, J., Olkkonen, V. M., Y …
These data support a novel model in which ORP4L is a cofactor of ITPR1, which increases ITPR1 sensitivity to IP(3) and enables ER Ca(2+) rel …