Spiers JP - Search Results

1

Regulation of the phosphoprotein phosphatase 2A system and its modulation during oxidative stress: A potential therapeutic target?

Elgenaidi IS, Spiers JP. Elgenaidi IS, et al. Among authors: spiers jp. Pharmacol Ther. 2019 Jun;198:68-89. doi: 10.1016/j.pharmthera.2019.02.011. Epub 2019 Feb 22. Pharmacol Ther. 2019. PMID: 30797822 Review.

2

Hypoxia modulates protein phosphatase 2A through HIF-1α dependent and independent mechanisms in human aortic smooth muscle cells and ventricular cardiomyocytes.

Elgenaidi IS, Spiers JP. Elgenaidi IS, et al. Among authors: spiers jp. Br J Pharmacol. 2019 Jun;176(11):1745-1763. doi: 10.1111/bph.14648. Epub 2019 Apr 22. Br J Pharmacol. 2019. PMID: 30825189 Free PMC article.

3

Protein phosphatase 2A regulation of markers of extracellular matrix remodelling in hepatocellular carcinoma cells: functional consequences for tumour invasion.

Ward MP, Spiers JP. Ward MP, et al. Among authors: spiers jp. Br J Pharmacol. 2017 May;174(10):1116-1130. doi: 10.1111/bph.13759. Epub 2017 Apr 7. Br J Pharmacol. 2017. PMID: 28239848 Free PMC article.

4

Receptor-mediated effects of endothelin on the L-type Ca++ current in ventricular cardiomyocytes.

Kelso EJ, Spiers JP, McDermott BJ, Scholfield CN, Silke B. Kelso EJ, et al. Among authors: spiers jp. J Pharmacol Exp Ther. 1998 Aug;286(2):662-9. J Pharmacol Exp Ther. 1998. PMID: 9694918

5

Okadaic acid induces matrix metalloproteinase-9 expression in fibroblasts: crosstalk between protein phosphatase inhibition and β-adrenoceptor signalling.

Rietz A, Volkov Y, Davies A, Hennessy M, Spiers JP. Rietz A, et al. Among authors: spiers jp. Br J Pharmacol. 2012 Jan;165(1):274-88. doi: 10.1111/j.1476-5381.2011.01559.x. Br J Pharmacol. 2012. PMID: 21718298 Free PMC article.

6

Long-term statin therapy in patients with systolic heart failure and normal cholesterol: effects on elevated serum markers of collagen turnover, inflammation, and B-type natriuretic peptide.

Abulhul E, McDonald K, Martos R, Phelan D, Spiers JP, Hennessy M, Baugh J, Watson C, O'Loughlin C, Ledwidge M. Abulhul E, et al. Among authors: spiers jp. Clin Ther. 2012 Jan;34(1):91-100. doi: 10.1016/j.clinthera.2011.11.002. Epub 2011 Dec 9. Clin Ther. 2012. PMID: 22154198 Clinical Trial.

7

Endothelin(A) receptor subtype mediates endothelin-induced contractility in left ventricular cardiomyocytes isolated from rabbit myocardium.

Kelso EJ, McDermott BJ, Silke B, Spiers JP. Kelso EJ, et al. Among authors: spiers jp. J Pharmacol Exp Ther. 2000 Sep;294(3):1047-52. J Pharmacol Exp Ther. 2000. PMID: 10945858

8

St Johns wort increases expression of P-glycoprotein: implications for drug interactions.

Hennessy M, Kelleher D, Spiers JP, Barry M, Kavanagh P, Back D, Mulcahy F, Feely J. Hennessy M, et al. Among authors: spiers jp. Br J Clin Pharmacol. 2002 Jan;53(1):75-82. doi: 10.1046/j.0306-5251.2001.01516.x. Br J Clin Pharmacol. 2002. PMID: 11849198 Free PMC article. Clinical Trial.

9

Myocardial expression of the endothelin system in endotoxin-treated rats.

Spiers JP, Dorman A, Allen JD, Kelso EJ, Silke B, McDermott BJ. Spiers JP, et al. J Cardiovasc Pharmacol. 2001 Aug;38(2):259-67. doi: 10.1097/00005344-200108000-00012. J Cardiovasc Pharmacol. 2001. PMID: 11483876

10

Duration of action and effect on baroreflex function of the anti-arrhythmic alpha 1 antagonist UK-52,046.

Spiers JP, Harron DW, Wilson R. Spiers JP, et al. J Pharm Pharmacol. 1991 Jan;43(1):70-2. doi: 10.1111/j.2042-7158.1991.tb05457.x. J Pharm Pharmacol. 1991. PMID: 1676070

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