Dinh JC - Search Results

1

Clinical Pharmacogenetics Implementation Consortium Guideline for Cytochrome P450 (CYP)2D6 Genotype and Atomoxetine Therapy.

Brown JT, Bishop JR, Sangkuhl K, Nurmi EL, Mueller DJ, Dinh JC, Gaedigk A, Klein TE, Caudle KE, McCracken JT, de Leon J, Leeder JS. Brown JT, et al. Among authors: dinh jc. Clin Pharmacol Ther. 2019 Jul;106(1):94-102. doi: 10.1002/cpt.1409. Epub 2019 Apr 13. Clin Pharmacol Ther. 2019. PMID: 30801677 Free PMC article.

2

Genetic determinants of fetal opiate exposure and risk of neonatal abstinence syndrome: Knowledge deficits and prospects for future research.

Lewis T, Dinh J, Leeder JS. Lewis T, et al. Clin Pharmacol Ther. 2015 Sep;98(3):309-20. doi: 10.1002/cpt.159. Epub 2015 Jul 22. Clin Pharmacol Ther. 2015. PMID: 26058918 Free PMC article. Review.

3

Characterization of Atomoxetine Biotransformation and Implications for Development of PBPK Models for Dose Individualization in Children.

Dinh JC, Pearce RE, Van Haandel L, Gaedigk A, Leeder JS. Dinh JC, et al. Drug Metab Dispos. 2016 Jul;44(7):1070-9. doi: 10.1124/dmd.116.069518. Epub 2016 Apr 6. Drug Metab Dispos. 2016. PMID: 27052878 Free PMC article.

4

Ten Years' Experience with the CYP2D6 Activity Score: A Perspective on Future Investigations to Improve Clinical Predictions for Precision Therapeutics.

Gaedigk A, Dinh JC, Jeong H, Prasad B, Leeder JS. Gaedigk A, et al. Among authors: dinh jc. J Pers Med. 2018 Apr 17;8(2):15. doi: 10.3390/jpm8020015. J Pers Med. 2018. PMID: 29673183 Free PMC article. Review.

5

The Respective Roles of CYP3A4 and CYP2D6 in the Metabolism of Pimozide to Established and Novel Metabolites.

Chapron BD, Dinh JC, Toren PC, Gaedigk A, Leeder JS. Chapron BD, et al. Among authors: dinh jc. Drug Metab Dispos. 2020 Nov;48(11):1113-1120. doi: 10.1124/dmd.120.000188. Epub 2020 Aug 26. Drug Metab Dispos. 2020. PMID: 32847865 Free PMC article.

6

Ontogeny of Scaling Factors for Pediatric Physiology-Based Pharmacokinetic Modeling and Simulation: Microsomal Protein Per Gram of Liver.

Leeder JS, Dinh JC, Gaedigk A, Staggs VS, Prasad B, Pearce RE. Leeder JS, et al. Among authors: dinh jc. Drug Metab Dispos. 2022 Jan;50(1):24-32. doi: 10.1124/dmd.121.000623. Epub 2021 Oct 22. Drug Metab Dispos. 2022. PMID: 34686522 Free PMC article.

7

The Impact of the CYP2D6 "Enhancer" Single Nucleotide Polymorphism on CYP2D6 Activity.

Dinh JC, Boone EC, Staggs VS, Pearce RE, Wang WY, Gaedigk R, Leeder JS, Gaedigk A. Dinh JC, et al. Clin Pharmacol Ther. 2022 Mar;111(3):646-654. doi: 10.1002/cpt.2469. Epub 2021 Nov 30. Clin Pharmacol Ther. 2022. PMID: 34716917 Free PMC article.

8

Impact of CYP2C:TG Haplotype on CYP2C19 Substrates Clearance In Vivo, Protein Content, and In Vitro Activity.

Zubiaur P, Soria-Chacartegui P, Boone EC, Prasad B, Dinh J, Wang WY, Zugbi S, Rodríguez-Lopez A, González-Iglesias E, Leeder JS, Abad-Santos F, Gaedigk A. Zubiaur P, et al. Clin Pharmacol Ther. 2023 Nov;114(5):1033-1042. doi: 10.1002/cpt.3012. Epub 2023 Aug 11. Clin Pharmacol Ther. 2023. PMID: 37528442 Free PMC article.

9

Potential contribution of cytochrome P450 2B6 to hepatic 4-hydroxycyclophosphamide formation in vitro and in vivo.

Raccor BS, Claessens AJ, Dinh JC, Park JR, Hawkins DS, Thomas SS, Makar KW, McCune JS, Totah RA. Raccor BS, et al. Among authors: dinh jc. Drug Metab Dispos. 2012 Jan;40(1):54-63. doi: 10.1124/dmd.111.039347. Epub 2011 Oct 5. Drug Metab Dispos. 2012. PMID: 21976622 Free PMC article.

10

Description of an Innovative Pediatric Individualized Therapeutics Clinic: Working toward Precision Drug Therapy.

Sandritter TL, Dinh JC, Wagner JA, Lowry JA. Sandritter TL, et al. Among authors: dinh jc. Children (Basel). 2019 Feb 25;6(2):35. doi: 10.3390/children6020035. Children (Basel). 2019. PMID: 30823616 Free PMC article.

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